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Nootropic Effects of C. melo and C. lanatus seed extracts
Joint Authors
Wahid, Shahana
Alqahtani, Ali
Khan, Rafeeq Alam
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Dementia and related conditions disturb the ability to perform routine life activities prohibiting a person from making appropriate decisions.
Seeds of Cucumis melo and Citrullus lanatus have been investigated extensively for various pharmacological properties; hence, considering the presence of bioactive compounds, it was assumed that these seed extracts may support the functioning of the central nervous system.
Thus, the present study was designed to investigate the short-term and long-term memory-enhancing effects of C.
melo and C.
lanatus seed extracts in mice by the Morris water maze (spatial learning and memory), stationary rod test, and passive avoidance tests (fear-motivated tests).
Ethanol extract of both seeds were prepared by standard procedure and given to animals in the doses of 50 mg/kg, 100 mg/kg, and 200 mg/kg.
The results were compared to standard drugs diazepam and imipramine given in the doses of 3 mg/kg and 30 mg/kg, respectively.
Extracts of both the seeds were found to possess significant memory and cognition-enhancing effects in mice when tested by passive avoidance, stationary rod, and water maze tests.
Results demonstrate memory and cognition-enhancing effects of these extracts which may be due to the presence of bioactive compounds in these seeds.
American Psychological Association (APA)
Wahid, Shahana& Alqahtani, Ali& Khan, Rafeeq Alam. 2020. Nootropic Effects of C. melo and C. lanatus seed extracts. BioMed Research International،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1137693
Modern Language Association (MLA)
Wahid, Shahana…[et al.]. Nootropic Effects of C. melo and C. lanatus seed extracts. BioMed Research International No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1137693
American Medical Association (AMA)
Wahid, Shahana& Alqahtani, Ali& Khan, Rafeeq Alam. Nootropic Effects of C. melo and C. lanatus seed extracts. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1137693
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137693