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Atypical Femoral Shaft Fractures in Female Bisphosphonate Users Were Associated with an Increased Anterolateral Femoral Bow and a Thicker Lateral Cortex: A Case-Control Study
Joint Authors
Moon, Young-Wan
Lim, Seung-Jae
Jang, Seung Pil
Yeo, Ingwon
So, Sang-Yeon
Kim, Keunbyuel
Park, Youn-Soo
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-28
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The purpose of our study was to investigate the radiographic characteristics of atypical femoral shaft fractures (AFSFs) in females with a particular focus on femoral bow and cortical thickness.
We performed a fracture location-, age-, gender-, and ethnicity-matched case-control study.
Forty-two AFSFs in 29 patients and 22 typical osteoporotic femoral shaft fractures in 22 patients were enrolled in AFSF group and control group, respectively.
With comparing demographics between two groups, radiographically measured femoral bow and cortical thicknesses of AFSF group were compared with control group.
All AFSF patients were females with a mean age of 74.4 years (range, 58–85 years).
All had a history of bisphosphonate (BP) use with a mean duration of 7.3 years (range 1–17 years).
Femoral bow of AFSF group was significantly higher than control group on both anteroposterior (AP) and lateral radiographs after age correction.
Mean femoral bow on an AP radiograph was 12.39°±5.38° in AFSF group and 3.97±3.62° in control group (P<0.0001).
Mean femoral bow on the lateral radiograph was 15.71°±5.62° in AFSF group and 10.72°±4.61° in control group (after age correction P=0.003).
And cortical thicknesses of AFSF group demonstrated marked disparity between tensile and compressive side of bowed femurs in this study.
An adjusted lateral cortical thickness was 10.5±1.4 mm in AFSF group and 8.1±1.3 mm in control group (after age correction P<0.0001) while medial cortical thickness of AFSF group was not statistically different from control group.
Correlation analysis showed that the lateral femoral bow on the AP radiograph was solely related to lateral CTI (R=0.378, P=0.002).
AFSFs in female BP users were associated with an increased anterolateral femoral bow and a thicker lateral cortex of femurs.
American Psychological Association (APA)
Jang, Seung Pil& Yeo, Ingwon& So, Sang-Yeon& Kim, Keunbyuel& Moon, Young-Wan& Park, Youn-Soo…[et al.]. 2017. Atypical Femoral Shaft Fractures in Female Bisphosphonate Users Were Associated with an Increased Anterolateral Femoral Bow and a Thicker Lateral Cortex: A Case-Control Study. BioMed Research International،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1137851
Modern Language Association (MLA)
Jang, Seung Pil…[et al.]. Atypical Femoral Shaft Fractures in Female Bisphosphonate Users Were Associated with an Increased Anterolateral Femoral Bow and a Thicker Lateral Cortex: A Case-Control Study. BioMed Research International No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1137851
American Medical Association (AMA)
Jang, Seung Pil& Yeo, Ingwon& So, Sang-Yeon& Kim, Keunbyuel& Moon, Young-Wan& Park, Youn-Soo…[et al.]. Atypical Femoral Shaft Fractures in Female Bisphosphonate Users Were Associated with an Increased Anterolateral Femoral Bow and a Thicker Lateral Cortex: A Case-Control Study. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1137851
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137851