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Long Noncoding RNAs Act as Novel Biomarkers for Hepatocellular Carcinoma: Progress and Prospects
Joint Authors
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-01
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and confers a poor prognosis.
Novel diagnostic or prognostic biomarkers and effective therapeutic targets for HCCs are urgently needed.
Currently, dozens of long noncoding RNAs (lncRNAs) have been identified as playing critical roles in cancer development and progression.
Advanced studies have shown that several well-known lncRNAs are dysregulated in HCC tissue as compared to adjacent noncancerous tissue.
Furthermore, highly stable cell-free circulating nucleic acids (cfCNAs), including lncRNAs, aberrantly expressed in the plasma of HCC patients, have been detected.
In this review, we focus on the most extensively investigated lncRNAs in HCC and discuss the potential of HCC-related lncRNAs as novel biomarkers for early diagnosis and prognosis.
American Psychological Association (APA)
Bao, Han& Su, Hongying. 2017. Long Noncoding RNAs Act as Novel Biomarkers for Hepatocellular Carcinoma: Progress and Prospects. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1137913
Modern Language Association (MLA)
Bao, Han& Su, Hongying. Long Noncoding RNAs Act as Novel Biomarkers for Hepatocellular Carcinoma: Progress and Prospects. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1137913
American Medical Association (AMA)
Bao, Han& Su, Hongying. Long Noncoding RNAs Act as Novel Biomarkers for Hepatocellular Carcinoma: Progress and Prospects. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1137913
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137913