Do miRNAs Play a Role in Fetal Growth Restriction? A Fresh Look to a Busy Corner
Joint Authors
Vitale, Salvatore Giovanni
Palmara, Vittorio Italo
Rapisarda, Agnese Maria Chiara
Granese, Roberta
Valenti, Gaetano
Sapia, Fabrizio
Rossetti, Diego
Chiofalo, Benito
La Rosa, Valentina Lucia
Triolo, Onofrio
Lagana, Antonio Simone
Vaiarelli, Alberto
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Placenta is the crucial organ for embryo and fetus development and plays a critical role in the development of fetal growth restriction (FGR).
There are increasing evidences on the role of microRNAs (miRNAs) in a variety of pregnancy-related complications such as preeclampsia and FGR.
More than 1880 miRNAs have been reported in humans and most of them are expressed in placenta.
In this paper, we aimed to review the current evidence about the topic.
According to retrieved data, controversial results about placental expression of miRNAs could be due (at least in part) to the different experimental methods used by different groups.
Despite the fact that several authors have demonstrated a relatively easy and feasible detection of some miRNAs in maternal whole peripheral blood, costs of these tests should be reduced in order to increase cohorts and have stronger evidence.
In this regard, we take the opportunity to solicit future studies on large cohort and adequate statistical power, in order to identify a panel of biomarkers on maternal peripheral blood for early diagnosis of FGR.
American Psychological Association (APA)
Chiofalo, Benito& Lagana, Antonio Simone& Vaiarelli, Alberto& La Rosa, Valentina Lucia& Rossetti, Diego& Palmara, Vittorio Italo…[et al.]. 2017. Do miRNAs Play a Role in Fetal Growth Restriction? A Fresh Look to a Busy Corner. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1137927
Modern Language Association (MLA)
Chiofalo, Benito…[et al.]. Do miRNAs Play a Role in Fetal Growth Restriction? A Fresh Look to a Busy Corner. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1137927
American Medical Association (AMA)
Chiofalo, Benito& Lagana, Antonio Simone& Vaiarelli, Alberto& La Rosa, Valentina Lucia& Rossetti, Diego& Palmara, Vittorio Italo…[et al.]. Do miRNAs Play a Role in Fetal Growth Restriction? A Fresh Look to a Busy Corner. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1137927
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137927