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Comparison of Different Contrast Agents in Detecting Cardiac Right-to-Left Shunt in Patients with a Patent Foramen Ovale during Contrast-Transthoracic Echocardiography
Joint Authors
Zhao, Enfa
Zhang, Yushun
Cheng, Gesheng
Li, Yang
Wang, Yingli
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The aim of this study is to evaluate the ability of two different contrast agents to detect cardiac right-to-left shunting in patients with a patent foramen ovale during contrast transthoracic echocardiography and transesophageal echocardiography.
Eighty-four patients who had migraines or experienced cryptogenic stroke were prospectively enrolled.
Contrast echocardiography of the right portion of the heart was performed using an injection of either (i) 8 ml of agitated saline, 1 ml of blood, and 1 ml of air (ASB) or (ii) 4 ml of vitamin B6 and 6 ml of sodium bicarbonate solution (VSBS).
All patients underwent contrast echocardiography with different contrast agents successively before undergoing transesophageal echocardiography.
The diagnostic sensitivity of VSBS and ASB for cardiac shunting diagnosis was 94.23% and 78.85%, respectively.
The diagnostic sensitivity in the VSBS group was significantly higher than that in the ASB group (χ2=5.283, P=0.022).
The observed semiquantitative shunt grading suggests that the positive rate in the VSBS group was higher than that in the ASB group (Z=-1.998, P=0.046).
The use of vitamin B6 and sodium bicarbonate solution as a TTE contrast agent yielded a high sensitivity compared with ASB.
However, further trials with large sample size are required to confirm this finding.
American Psychological Association (APA)
Zhao, Enfa& Cheng, Gesheng& Zhang, Yushun& Li, Yang& Wang, Yingli. 2017. Comparison of Different Contrast Agents in Detecting Cardiac Right-to-Left Shunt in Patients with a Patent Foramen Ovale during Contrast-Transthoracic Echocardiography. BioMed Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1137940
Modern Language Association (MLA)
Zhao, Enfa…[et al.]. Comparison of Different Contrast Agents in Detecting Cardiac Right-to-Left Shunt in Patients with a Patent Foramen Ovale during Contrast-Transthoracic Echocardiography. BioMed Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1137940
American Medical Association (AMA)
Zhao, Enfa& Cheng, Gesheng& Zhang, Yushun& Li, Yang& Wang, Yingli. Comparison of Different Contrast Agents in Detecting Cardiac Right-to-Left Shunt in Patients with a Patent Foramen Ovale during Contrast-Transthoracic Echocardiography. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1137940
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137940