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Advancements in Developing Strategies for Sterilizing and Functional HIV Cures
Joint Authors
Lu, Lu
Jiang, Shibo
Xu, Wei
Li, Haoyang
Wang, Qian
Hua, Chen
Zhang, Hanzhen
Li, Weihua
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-26
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Combined antiretroviral therapy (cART) has been successful in prolonging lifespan and reducing mortality of patients infected with human immunodeficiency virus (HIV).
However, the eradication of latent HIV reservoirs remains a challenge for curing HIV infection (HIV cure) because of HIV latency in primary memory CD4+ T cells.
Currently, two types of HIV cures are in development: a “sterilizing cure” and a “functional cure.” A sterilizing cure refers to the complete elimination of replication-competent proviruses in the body, while a functional cure refers to the long-term control of HIV replication without treatment.
Based on these concepts, significant progress has been made in different areas.
This review focuses on recent advancements and future prospects for HIV cures.
American Psychological Association (APA)
Xu, Wei& Li, Haoyang& Wang, Qian& Hua, Chen& Zhang, Hanzhen& Li, Weihua…[et al.]. 2017. Advancements in Developing Strategies for Sterilizing and Functional HIV Cures. BioMed Research International،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1137947
Modern Language Association (MLA)
Xu, Wei…[et al.]. Advancements in Developing Strategies for Sterilizing and Functional HIV Cures. BioMed Research International No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1137947
American Medical Association (AMA)
Xu, Wei& Li, Haoyang& Wang, Qian& Hua, Chen& Zhang, Hanzhen& Li, Weihua…[et al.]. Advancements in Developing Strategies for Sterilizing and Functional HIV Cures. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1137947
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137947