Histopathological and Reproductive Evaluation in Male Rats Fed Jatropha curcas Seed Cake with or without Alkaline Hydrolysis and Subjected to Heat Treatment
Joint Authors
Maiorka, Paulo
Teixeira Sousa Moura, Laiane
Palomaris Mariano Souza, Domenica
Mendonça, Simone
de Aquino Ribeiro, José Antônio
Fernandes Sousa, Luciano
Tony Ramos, Adriano
de Araújo, Vera Lúcia
Mayumi Maruo, Viviane
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-23
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Jatropha curcas cake, a by-product of biodiesel production, is rich in protein and has potential to be used in livestock feed; however, the presence of antinutritional factors and phorbol esters limits its use.
Thus, this study investigated toxicological and reproductive effects in male Wistar rats after subchronic exposure to J.
curcas cake subjected to detoxification procedures.
Rats were divided into seven groups (n=10) and treated for 60 days.
The control group received commercial feed, while experimental groups received a diet containing 5% J.
curcas cake nonhydrolyzed or hydrolyzed with 5 M NaOH.
The cakes were unwashed or washed with ethanol or water and were autoclaved at 121°C for 30 minutes.
Alkaline hydrolysis combined with ethanol washing decreased the phorbol ester concentration in the cake by 98%.
Histopathological findings included diffuse degeneration of the liver and edema around the pulmonary vessels in the nonhydrolyzed groups.
In addition, nontreated females mated with males of nonhydrolyzed unwashed group showed a decreased number of live fetuses and an increased placental weight.
There were no signs of toxicity in rats given hydrolyzed cakes washed and unwashed, indicating that alkaline hydrolysis associated with heat treatment is an efficient method for detoxification of the J.
curcas cake.
American Psychological Association (APA)
Teixeira Sousa Moura, Laiane& Palomaris Mariano Souza, Domenica& Mendonça, Simone& de Aquino Ribeiro, José Antônio& Fernandes Sousa, Luciano& Tony Ramos, Adriano…[et al.]. 2017. Histopathological and Reproductive Evaluation in Male Rats Fed Jatropha curcas Seed Cake with or without Alkaline Hydrolysis and Subjected to Heat Treatment. BioMed Research International،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1137952
Modern Language Association (MLA)
Teixeira Sousa Moura, Laiane…[et al.]. Histopathological and Reproductive Evaluation in Male Rats Fed Jatropha curcas Seed Cake with or without Alkaline Hydrolysis and Subjected to Heat Treatment. BioMed Research International No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1137952
American Medical Association (AMA)
Teixeira Sousa Moura, Laiane& Palomaris Mariano Souza, Domenica& Mendonça, Simone& de Aquino Ribeiro, José Antônio& Fernandes Sousa, Luciano& Tony Ramos, Adriano…[et al.]. Histopathological and Reproductive Evaluation in Male Rats Fed Jatropha curcas Seed Cake with or without Alkaline Hydrolysis and Subjected to Heat Treatment. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1137952
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1137952