Prevalence of Hyperhomocysteinaemia and Associated Factors among Ethiopian Adult Population in a 2015 National Survey
Joint Authors
Chala, Feyissa
Getahun, Tigist
Sileshi, Meron
Nigassie, Bikila
Geto, Zeleke
Ashibire, Genet
Gelibo, Terefe
Teferra, Solomon
Seifu, Daniel
Sitotaw, Yohannes
Bekele, Abebe
Abate, Ebba
Baye, Kaleab
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-11
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Hyperhomocysteinaemia (HHcy) is an independent risk factor for major cardiovascular diseases, but data on the prevalence and predictors of HHcy in low- and middle-income countries like Ethiopia are scant.
The aim of this study was to estimate the prevalence of HHcy and associated risk factors in the Ethiopian adult population.
A cross-sectional survey on risks of noncommunicable diseases (NCDs) using the STEPwise approach to surveillance (STEPS) survey was conducted between April and June 2015.
A total of 4,175 study participants were surveyed.
Serum homocysteine (Hcy) and metabolic profile were determined using Cobas Integra 400 Plus and CardioChek PA analyzer, respectively.
Factors associated with HHcy were determined using logistic regression.
The mean serum tHcy concentration was 14.6 μmol/L, with 16.4 μmol/L in males and 13.4 μmol/L in females.
Overall, 38% had HHcy, with figures in males (49%) higher than females (30%).
Increased age, being male, and high blood pressure and/or taking blood pressure medication, as well as low consumption of fruit and/or vegetables, were independent risk factors for HHcy.
In conclusion, the prevalence of HHcy among the adult Ethiopian population is alarmingly high.
Improving diets through the promotion of fruit and vegetable consumption is needed to reduce the risk of NCDs.
American Psychological Association (APA)
Chala, Feyissa& Getahun, Tigist& Sileshi, Meron& Nigassie, Bikila& Geto, Zeleke& Ashibire, Genet…[et al.]. 2020. Prevalence of Hyperhomocysteinaemia and Associated Factors among Ethiopian Adult Population in a 2015 National Survey. BioMed Research International،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1138019
Modern Language Association (MLA)
Chala, Feyissa…[et al.]. Prevalence of Hyperhomocysteinaemia and Associated Factors among Ethiopian Adult Population in a 2015 National Survey. BioMed Research International No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1138019
American Medical Association (AMA)
Chala, Feyissa& Getahun, Tigist& Sileshi, Meron& Nigassie, Bikila& Geto, Zeleke& Ashibire, Genet…[et al.]. Prevalence of Hyperhomocysteinaemia and Associated Factors among Ethiopian Adult Population in a 2015 National Survey. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1138019
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138019