Effect of Excess Iodide Intake on Salivary Glands in a Swiss Albino Mice Model
Joint Authors
Ross, Gloria Romina
Fabersani, Emanuel
Russo, Matías
Gómez, Alba
Japaze, Hugo
Gauffin Cano, Paola
Gonzalez, Silvia N.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-08
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Iodine is an important micronutrient required for nutrition.
Excess iodine has adverse effects on thyroid, but there is not enough information regarding its effect on salivary glands.
In addition to food and iodized salt, skin disinfectants and maternal nutritional supplements contain iodide, so its intake could be excessive during pregnancy, lactation, and infancy.
The aim of this work was to evaluate the effect of excess iodide ingestion on salivary glands during mating, gestation, lactation, and postweaning period in mouse.
During assay, mice were allocated into groups: control and treatment groups (received distilled water with NaI 1 mg/mL).
Water intake, glandular weight, and histology were analyzed.
Treatment groups showed an increase in glandular weight and a significantly (p < 0.05) higher water intake than control groups.
Lymphocyte infiltration was observed in animals of treatment groups, while there was no infiltration in glandular sections of control groups.
Results demonstrated that a negative relationship could exist between iodide excess and salivary glands.
This work is novel evidence that high levels of iodide intake could induce mononuclear infiltration in salivary glands.
These results should be considered, especially in pregnant/lactating women, to whom a higher iodine intake is usually recommended.
American Psychological Association (APA)
Ross, Gloria Romina& Fabersani, Emanuel& Russo, Matías& Gómez, Alba& Japaze, Hugo& Gonzalez, Silvia N.…[et al.]. 2017. Effect of Excess Iodide Intake on Salivary Glands in a Swiss Albino Mice Model. BioMed Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1138029
Modern Language Association (MLA)
Ross, Gloria Romina…[et al.]. Effect of Excess Iodide Intake on Salivary Glands in a Swiss Albino Mice Model. BioMed Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1138029
American Medical Association (AMA)
Ross, Gloria Romina& Fabersani, Emanuel& Russo, Matías& Gómez, Alba& Japaze, Hugo& Gonzalez, Silvia N.…[et al.]. Effect of Excess Iodide Intake on Salivary Glands in a Swiss Albino Mice Model. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1138029
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138029