Risk Factors of Portal Vein Thrombosis after Devascularization Treatment in Patients with Liver Cirrhosis: A Nested Case-Control Study
Joint Authors
Wang, Jian
Chen, Shiyao
Lu, Shenxin
Hu, Guohua
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-27
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Background and Aim.
To investigate the incidence of portal vein thrombosis (PVT) after devascularization treatment and to explore the risk factors of perioperative PVT and PVT diagnosed during the follow-up period after surgery.
Methods.
We retrospectively reviewed medical records from cirrhosis patients who underwent devascularization for the treatment of portal hypertension in our hospital between January 1, 2008, and December 20, 2014.
Patients were followed up to investigate the PVT incidence at different times after surgery.
Patients were divided into two groups (PVT, no PVT), and the risk factors for PVT after surgery were determined.
Results.
Until October 16, 2015, the median follow-up time of the 124 patients enrolled into this study was 41.43 months (range, 5.47–95.30 months).
61 patients had perioperative PVT, and 21 (16.94%) patients had PVT diagnosed during the follow-up period.
Those who had lower preoperative white blood cell counts, larger preoperative portal vein trunk diameter, and no gastric varices were more likely to have perioperative thrombosis.
In those without perioperative PVT, a history of hypertension, higher grade of splenomegaly, and higher preoperative levels of creatinine were independent predictors of PVT occurrence during the follow-up period.
Conclusions.
The risk factors for perioperative PVT in cirrhotic patients after devascularization were lower preoperative white blood cell count and larger portal vein trunk diameter, with no gastric varices.
A history of hypertension, a larger spleen, and higher preoperative creatinine level are independent predictors of PVT during follow-up after surgery in patients without perioperative PVT.
American Psychological Association (APA)
Lu, Shenxin& Hu, Guohua& Chen, Shiyao& Wang, Jian. 2020. Risk Factors of Portal Vein Thrombosis after Devascularization Treatment in Patients with Liver Cirrhosis: A Nested Case-Control Study. BioMed Research International،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1138190
Modern Language Association (MLA)
Lu, Shenxin…[et al.]. Risk Factors of Portal Vein Thrombosis after Devascularization Treatment in Patients with Liver Cirrhosis: A Nested Case-Control Study. BioMed Research International No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1138190
American Medical Association (AMA)
Lu, Shenxin& Hu, Guohua& Chen, Shiyao& Wang, Jian. Risk Factors of Portal Vein Thrombosis after Devascularization Treatment in Patients with Liver Cirrhosis: A Nested Case-Control Study. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1138190
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138190