Clinical Characteristics and Surgical Management of Gastrointestinal Schwannomas
Joint Authors
Wu, Xin
Li, Binglu
Zheng, Chaoji
He, Xiaodong
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objectives.
Schwannomas are tumors arising from Schwan cells of the neural sheath.
Gastrointestinal schwannomas (GS) are rare and easily confused with a heterogeneous group of neuroectodermal or mesenchymal neoplasms.
The aim of the present study is to analyze the clinicopathological features, surgical management methods, and long-term prognoses of GS patients.
Methods.
Between August 2004 and July 2019, 51 patients with GS were treated at the Peking Union Medical College Hospital.
The medical records were reviewed retrospectively.
A database containing demographic characteristics, clinical symptoms, imaging tests, operation details, pathological results, and prognoses was constructed and analyzed.
Results.
GS accounted for 2.0% of all schwannomas.
The cohort comprised 19 men (37.3%) and 32 women (62.7%).
The mean age was 55.7±11.4 years.
The most common symptom was abdominal pain (29.4%).
Twenty-seven patients (52.9%) were asymptomatic and diagnosed incidentally.
The most common tumor location of GS was the stomach (90.2%).
S-100 had the highest positive rate (100%) in immunohistochemical staining.
Forty-six patients (90.2%) were followed-up at a mean period of 49.5±41.4 months.
Forty-four patients (95.7%) survived without tumor, 1 patient survived with tumor, and 1 patient died.
The 5-year cumulative overall survival rate and cumulative disease-free survival rate were 97.5% and 95.2%, respectively.
Conclusion.
GS are rare gastrointestinal tumors with favorable prognoses after surgical resection.
Stomach is the most common site.
Definitive diagnosis is determined by postoperative pathology.
S-100 expression has diagnostic significance.
American Psychological Association (APA)
Wu, Xin& Li, Binglu& Zheng, Chaoji& He, Xiaodong. 2020. Clinical Characteristics and Surgical Management of Gastrointestinal Schwannomas. BioMed Research International،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1138200
Modern Language Association (MLA)
Wu, Xin…[et al.]. Clinical Characteristics and Surgical Management of Gastrointestinal Schwannomas. BioMed Research International No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1138200
American Medical Association (AMA)
Wu, Xin& Li, Binglu& Zheng, Chaoji& He, Xiaodong. Clinical Characteristics and Surgical Management of Gastrointestinal Schwannomas. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1138200
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138200