Comparison of Chemical Composition and Bioactivities of Essential Oils from Fresh and Dry Rhizomes of Zingiber zerumbet (L.) Smith
Joint Authors
Tian, Minyi
Wu, Xianghuan
Hong, Yi
Wang, Huijuan
Deng, Guodong
Zhou, Ying
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-11
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The chemical constituents and the antioxidant, antimicrobial, and cytotoxic activities of fresh rhizome essential oil (FR-EO) and dry rhizome essential oil (DR-EO) of Zingiber zerumbet (L.) Smith obtained from Southwest China were compared.
Zerumbone was the predominant component in both FR-EO and DR-EO (75.0% and 41.9%, respectively).
FR-EO, DR-EO, and zerumbone were all demonstrated to have significant antimicrobial capacity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Proteus vulgaris, with minimum inhibitory concentration (MIC) ranging from 31.25 to 156.25 μg/mL and minimum bactericidal concentration (MBC) ranging from 62.50 to 625.00 μg/mL.
Zerumbone showed the strongest antimicrobial potential against all tested microorganisms compared with the fresh and dry rhizome essential oils.
FR-EO was found to be more active than DR-EO against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Proteus vulgaris.
FR-EO, DR-EO, and zerumbone all showed significant cytotoxic activity against K562, PC-3, and A549 human tumor cell lines in a time- and concentration-dependent manner.
Zerumbone exhibited the strongest antiproliferative activity against all tested human tumor cell lines with an IC50 of 4.21–11.09 μg/mL for 72 h incubation, as compared with the fresh and dry rhizome oils.
The cytotoxic activity of FR-EO (IC50: 10.48–14.51 μg/mL for 72 h) was found to be significantly higher (p<0.05) than that of DR-EO (IC50: 13.83–33.24 μg/mL for 72 h).
FR-EO, DR-EO, and zerumbone exhibited selective cytotoxic activity to tumor cells, with a significantly low cytotoxicity to normal cells (MRC-5, IC50: 56.98–147.29 μg/mL).
However, FR-EO, DR-EO, and zerumbone all exhibited weak free-radical-scavenging activity according to DPPH and ABTS analysis.
The findings highlighted in this study show that FR-EO provides appreciably higher content of the bioactive compound, zerumbone, and has higher antimicrobial and cytotoxic properties than DR-EO.
Thus, fresh Z.
zerumbet rhizome should be preferred in cosmetic, food, and pharmaceutical applications.
American Psychological Association (APA)
Tian, Minyi& Wu, Xianghuan& Hong, Yi& Wang, Huijuan& Deng, Guodong& Zhou, Ying. 2020. Comparison of Chemical Composition and Bioactivities of Essential Oils from Fresh and Dry Rhizomes of Zingiber zerumbet (L.) Smith. BioMed Research International،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1138216
Modern Language Association (MLA)
Tian, Minyi…[et al.]. Comparison of Chemical Composition and Bioactivities of Essential Oils from Fresh and Dry Rhizomes of Zingiber zerumbet (L.) Smith. BioMed Research International No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1138216
American Medical Association (AMA)
Tian, Minyi& Wu, Xianghuan& Hong, Yi& Wang, Huijuan& Deng, Guodong& Zhou, Ying. Comparison of Chemical Composition and Bioactivities of Essential Oils from Fresh and Dry Rhizomes of Zingiber zerumbet (L.) Smith. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1138216
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138216