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Labor Induction with Orally Administrated Misoprostol: A Retrospective Cohort Study
Joint Authors
Wallstrom, Tove
Jarnbert-Pettersson, Hans
Stenson, David
Akerud, Helena
Darj, Elisabeth
Gemzell-Danielsson, Kristina
Wiberg-Itzel, Eva
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-18
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Introduction.
One great challenge in obstetric care is labor inductions.
Misoprostol has advantages in being cheap and stable at room temperature and available in resource-poor settings.
Material and Methods.
Retrospective cohort study of 4002 singleton pregnancies with a gestational age ≥34 w at Sodersjukhuset, Stockholm, during 2009-2010 and 2012-2013.
Previously used methods of labor induction were compared with misoprostol given as a solution to drink, every second hour.
Main outcome is as follows: Cesarean Section (CS) rate, acid-base status in cord blood, Apgar score < 7,5′, active time of labor, and blood loss > 1500 ml (PPH).
Results.
The proportion of CS decreased from 26% to 17% when orally given solution of misoprostol was introduced at the clinic (p<0.001).
No significant difference in the frequency of low Apgar score (p=0.3), low aPh in cord blood (p=0.1), or PPH (p=0.4) between the different methods of induction was studied.
After adjustment for different risk factor for CS the only method of induction which was associated with CS was dinoproston⁎⁎ (Propess®) (aor = 2.9 (1.6–5.2)).
Conclusion.
Induction of labor with misoprostol, given as an oral solution to drink every second hour, gives a low rate of CS, without affecting maternal or fetal outcome.
American Psychological Association (APA)
Wallstrom, Tove& Jarnbert-Pettersson, Hans& Stenson, David& Akerud, Helena& Darj, Elisabeth& Gemzell-Danielsson, Kristina…[et al.]. 2017. Labor Induction with Orally Administrated Misoprostol: A Retrospective Cohort Study. BioMed Research International،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1138243
Modern Language Association (MLA)
Wallstrom, Tove…[et al.]. Labor Induction with Orally Administrated Misoprostol: A Retrospective Cohort Study. BioMed Research International No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1138243
American Medical Association (AMA)
Wallstrom, Tove& Jarnbert-Pettersson, Hans& Stenson, David& Akerud, Helena& Darj, Elisabeth& Gemzell-Danielsson, Kristina…[et al.]. Labor Induction with Orally Administrated Misoprostol: A Retrospective Cohort Study. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1138243
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138243