Validation and Comparison of Aneurysmal Subarachnoid Hemorrhage Grading Scales in Angiogram-Negative Subarachnoid Hemorrhage Patients

Joint Authors

Zhang, Jianmin
Fang, Yuanjian
Xu, Shenbin
Lu, Jianan
Wu, Haijian
Zheng, Jingwei
Lenahan, Cameron
Cao, Yang
Chen, Sheng
Wang, Zefeng

Source

BioMed Research International

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-03-02

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Medicine

Abstract EN

Numerous grading scales have been proposed to predict the outcome of aneurysmal subarachnoid hemorrhage (SAH); however, these have not been validated in angiogram-negative SAH patients.

In this study, we aim to validate and compare the aneurysmal SAH grading scales in angiogram-negative SAH patients.

There were 190 angiogram-negative SAH patients analyzed from January 2014 to December 2015.

The outcomes were measured by delayed cerebral ischemia (DCI) and poor outcome (defined as modified Rankin Scale (mRS) 3-6 or 4-6).

The predictive performance of the grading scales was assessed via evaluation of distribution, trend, association, and discrimination.

In regard to the distribution, none of the patients were categorized as HAIR 8 and SAH score 8.

Both grading scales indicated a significant trend between scores and outcome (P<0.05), and association with the outcome (OR>1).

The modified Fisher Scale (mFS), World Federation of Neurosurgical Societies scale (WFNS), and combined scores VASOGRADE and HAIR showed good predictive accuracy (area under the curve AUC>0.750) for DCI.

The predictive accuracy in each scale performed well in predicting poor outcome, with the exception of mFS and the Subarachnoid hemorrhage Early Brain Edema Score (SEBES).

However, the mFS performed with increased accuracy when predicting mRS 4-6.

The VASOGRADE, HAIR, and WFNS may be valuable prognostic tools for predicting both DCI and poor outcome.

The mFS can be applicable for predicting DCI and mRS 4-6.

The SAH score and the Hunt-Hess were also optimal for predicting poor outcome.

The predictive performance of SEBES was relatively poor compared to the other scales.

American Psychological Association (APA)

Fang, Yuanjian& Xu, Shenbin& Lu, Jianan& Wu, Haijian& Zheng, Jingwei& Lenahan, Cameron…[et al.]. 2020. Validation and Comparison of Aneurysmal Subarachnoid Hemorrhage Grading Scales in Angiogram-Negative Subarachnoid Hemorrhage Patients. BioMed Research International،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1138244

Modern Language Association (MLA)

Fang, Yuanjian…[et al.]. Validation and Comparison of Aneurysmal Subarachnoid Hemorrhage Grading Scales in Angiogram-Negative Subarachnoid Hemorrhage Patients. BioMed Research International No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1138244

American Medical Association (AMA)

Fang, Yuanjian& Xu, Shenbin& Lu, Jianan& Wu, Haijian& Zheng, Jingwei& Lenahan, Cameron…[et al.]. Validation and Comparison of Aneurysmal Subarachnoid Hemorrhage Grading Scales in Angiogram-Negative Subarachnoid Hemorrhage Patients. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1138244

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1138244