Integrated Stress Response as a Therapeutic Target for CNS Injuries

Joint Authors

Romero-Ramírez, Lorenzo
Nieto-Sampedro, Manuel
Barreda-Manso, M. Asunción

Source

BioMed Research International

Issue

Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2017-04-27

Country of Publication

Egypt

No. of Pages

7

Main Subjects

Medicine

Abstract EN

Central nervous system (CNS) injuries, caused by cerebrovascular pathologies or mechanical contusions (e.g., traumatic brain injury, TBI) comprise a diverse group of disorders that share the activation of the integrated stress response (ISR).

This pathway is an innate protective mechanism, with encouraging potential as therapeutic target for CNS injury repair.

In this review, we will focus on the progress in understanding the role of the ISR and we will discuss the effects of various small molecules that target the ISR on different animal models of CNS injury.

American Psychological Association (APA)

Romero-Ramírez, Lorenzo& Nieto-Sampedro, Manuel& Barreda-Manso, M. Asunción. 2017. Integrated Stress Response as a Therapeutic Target for CNS Injuries. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1138299

Modern Language Association (MLA)

Romero-Ramírez, Lorenzo…[et al.]. Integrated Stress Response as a Therapeutic Target for CNS Injuries. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1138299

American Medical Association (AMA)

Romero-Ramírez, Lorenzo& Nieto-Sampedro, Manuel& Barreda-Manso, M. Asunción. Integrated Stress Response as a Therapeutic Target for CNS Injuries. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1138299

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1138299