Collective Housing of Mice of Different Age Groups before Maturity Affects Mouse Behavior
Joint Authors
Okamoto, Motoi
Suemitsu, Shunsuke
Murakami, Shinji
Kitamura, Naoya
Wani, Kenta
Ishihara, Takeshi
Matsumoto, Yosuke
Ueno, Hiroshi
Takahashi, Yu
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-12
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Background.
Although population housing is recommended by many animal management and ethical guidelines, the effect of collective housing of mice of different age groups on mouse behavior has not been clarified.
Since the development of the central nervous system continues to occur before sexual maturation, the stress of social ranking formation among male individuals in mixed housing conditions can affect postmaturation behavior.
To assess these effects, sexually immature mice of different ages were housed in the same cage and a series of behavioral tests were performed after maturation.
Results.
The findings for three groups of mice—junior mice housed with older mice, senior mice housed with younger mice, and mice housed with other mice of the same age—were compared.
Junior mice showed higher body weight and activity as well as lower grip strength and anxiety-like behaviors than other mice.
In contrast, senior mice showed lower body temperature and increased aggression, antinociceptive effect, and home-cage activity in the dark period in comparison with other mice.
Conclusions.
Thus, combined housing of immature mice of different age groups affects mouse behavior after maturation.
Appropriate prematuration housing conditions are crucial to eliminate the uncontrollable bias caused by age-related social stratification.
American Psychological Association (APA)
Ueno, Hiroshi& Suemitsu, Shunsuke& Murakami, Shinji& Kitamura, Naoya& Wani, Kenta& Takahashi, Yu…[et al.]. 2020. Collective Housing of Mice of Different Age Groups before Maturity Affects Mouse Behavior. Behavioural Neurology،Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1138409
Modern Language Association (MLA)
Ueno, Hiroshi…[et al.]. Collective Housing of Mice of Different Age Groups before Maturity Affects Mouse Behavior. Behavioural Neurology No. 2020 (2020), pp.1-13.
https://search.emarefa.net/detail/BIM-1138409
American Medical Association (AMA)
Ueno, Hiroshi& Suemitsu, Shunsuke& Murakami, Shinji& Kitamura, Naoya& Wani, Kenta& Takahashi, Yu…[et al.]. Collective Housing of Mice of Different Age Groups before Maturity Affects Mouse Behavior. Behavioural Neurology. 2020. Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1138409
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138409