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Establishment and Application of Prostate Cancer Circulating Tumor Cells in the Era of Precision Medicine
Joint Authors
Joung, Jae Young
Seo, Ho Kyung
Chung, Jinsoo
Lee, Kang Hyun
Kim, Sung Han
Suh, Yoon Seok
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-05
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Prostate cancer (PC) is the second most common cancer in men and is the fifth leading cause of cancer-related deaths worldwide.
Additionally, there is concern for overdiagnosis and overtreatment of PC.
Thus, selection of an appropriate candidate for active surveillance as well as more accurate and less invasive tools for monitoring advanced PC is required.
Circulating tumor cells (CTCs) have emerged as a liquid biopsy tool; there have been several reports on its role, technologies, and applications to various cancers, including PC.
Liquid biopsy using CTCs has been gaining attention as a minimal invasive tool for investigation of biomarkers and for prognosis and assessment of response to therapies in patients with PC.
Because of the lower invasiveness of liquid biopsy using CTCs, it can be performed more frequently; accordingly, personalized disease status can be successively determined at serial time points.
CTC analysis enables detection of genomic alterations, which is drug-targetable, and it is a potential tool for monitoring response to therapeutic agents in patients with PC.
This review focuses on the characteristics, technologies for analysis, and advantages and disadvantages of CTCs as a liquid biopsy tool and their application in PC.
Finally, we propose future directions of CTCs.
American Psychological Association (APA)
Suh, Yoon Seok& Joung, Jae Young& Kim, Sung Han& Seo, Ho Kyung& Chung, Jinsoo& Lee, Kang Hyun. 2017. Establishment and Application of Prostate Cancer Circulating Tumor Cells in the Era of Precision Medicine. BioMed Research International،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1138449
Modern Language Association (MLA)
Suh, Yoon Seok…[et al.]. Establishment and Application of Prostate Cancer Circulating Tumor Cells in the Era of Precision Medicine. BioMed Research International No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1138449
American Medical Association (AMA)
Suh, Yoon Seok& Joung, Jae Young& Kim, Sung Han& Seo, Ho Kyung& Chung, Jinsoo& Lee, Kang Hyun. Establishment and Application of Prostate Cancer Circulating Tumor Cells in the Era of Precision Medicine. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1138449
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138449