Methylated Flavonols from Amomum koenigii J.F.Gmel. and Their Antimicrobial and Antioxidant Activities
Joint Authors
Phan, Minh Giang
Do, Thi Viet Huong
Nguyen, Quoc Binh
Source
Biochemistry Research International
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Methylated flavonols form a special group with modulating biological activities in comparison with kaempferol and quercetin.
The present study isolated ten compounds including two kaempferol methyl ethers: 5-hydroxy-3,7,4′-trimethoxyflavone (1), 3-hydroxy-5,7,4′-trimethoxyflavone (6); four quercetin methyl ethers: retusin (5-hydroxy-3,7,3′,4′-tetramethoxyflavone) (4), 3,5-dihydroxy-7,3′,4′-trimethoxyflavone (5), 3,4′-dihydroxy-5,7,3′-trimethoxyflavone (7), and 3,5,7,3′,4′-pentamethoxyflavone (9); β-sitosterol (2); 5-hydroxy-1-(4′-hydroxyphenyl)eicosan-3-one (3); p-hydroquinone (8); and vanillic acid (10) from the rhizomes and fruit of Amomum koenigii J.F.Gmel.
(Zingiberaceae).
Their structures were determined by MS, NMR, and X-ray spectroscopic techniques.
Among the methylated flavonols, 1, 4–7, and 9 were isolated for the first time from the rhizomes, while 1, 4, and 5 were isolated from the fruit.
Compounds 2, 3, 7, 8, and 10 were reported for the first time from the species.
Three main methylated flavonols 1, 4, and 5 were quantitatively analyzed in the rhizomes of A.
koenigii by RP-HPLC-DAD; their contents were determined to be 1.81% (1), 1.38% (4), and 1.76% (5).
The antimicrobial assay against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, Staphylococcus aureus, Aspergillus niger, Fusarium oxysporum, Candida albicans, and Saccharomyces cerevisiae and antioxidant DPPH scavenging test were performed for the isolated methylated flavonols.
American Psychological Association (APA)
Phan, Minh Giang& Do, Thi Viet Huong& Nguyen, Quoc Binh. 2020. Methylated Flavonols from Amomum koenigii J.F.Gmel. and Their Antimicrobial and Antioxidant Activities. Biochemistry Research International،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1138450
Modern Language Association (MLA)
Phan, Minh Giang…[et al.]. Methylated Flavonols from Amomum koenigii J.F.Gmel. and Their Antimicrobial and Antioxidant Activities. Biochemistry Research International No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1138450
American Medical Association (AMA)
Phan, Minh Giang& Do, Thi Viet Huong& Nguyen, Quoc Binh. Methylated Flavonols from Amomum koenigii J.F.Gmel. and Their Antimicrobial and Antioxidant Activities. Biochemistry Research International. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1138450
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138450