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Association between Visceral Fat and Bone Mineral Density in Both Male and Female Patients with Adult Growth Hormone Deficiency
Joint Authors
Yang, Gangyi
Li, Linman
Zhong, Li
Zheng, Xiaoya
You, Wenyi
Wang, Yunting
Yu, Jihui
Wu, Xun
Ren, Wei
Source
Biochemistry Research International
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-06
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aim.
Adult growth hormone deficiency (AGHD) is associated with an increased risk of fractures.
The interactions between various body composition and bone are known to be complex in nature.
However, very few studies have examined this crosstalk in AGHD.
In this study, we sought to investigate the relationship between various parameters of body composition and bone mineral density (BMD) as well as determine the role of visceral fat in determining the bone mass in patients with AGHD.
Methods.
We conducted a cross-sectional study on 57 patients with AGHD.
Anthropometry, biochemistry, and analysis of body composition and BMD were performed according to standard protocols.
Male and female patients were classified into those with osteoporosis and those without osteoporosis (normal subjects and patients with osteopenia).
Further, we analyzed the correlation between the BMD and measurements obtained for various body composition parameters in male and female AGHD patients.
Results.
Our findings indicated that among female AGHD patients, those with osteoporosis had a significantly higher levels of fat mass (FM) and visceral adipose tissue mass (VATM) (both, P<0.05) than those without osteoporosis.
Further, Pearson correlation analysis showed that the values of age, body mass index (BMI), FM, and VATM correlated negatively with BMD in women with AGHD (all P<0.05); however, this association was not noted in men.
After adjusting for the other covariates, VATM was found to be independently correlated with the BMD in female patients with AGHD.
Conclusions.
A close correlation was noted between VATM and BMD in female patients with AGHD.
American Psychological Association (APA)
Li, Linman& Zhong, Li& Zheng, Xiaoya& You, Wenyi& Wang, Yunting& Yu, Jihui…[et al.]. 2020. Association between Visceral Fat and Bone Mineral Density in Both Male and Female Patients with Adult Growth Hormone Deficiency. Biochemistry Research International،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1138451
Modern Language Association (MLA)
Li, Linman…[et al.]. Association between Visceral Fat and Bone Mineral Density in Both Male and Female Patients with Adult Growth Hormone Deficiency. Biochemistry Research International No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1138451
American Medical Association (AMA)
Li, Linman& Zhong, Li& Zheng, Xiaoya& You, Wenyi& Wang, Yunting& Yu, Jihui…[et al.]. Association between Visceral Fat and Bone Mineral Density in Both Male and Female Patients with Adult Growth Hormone Deficiency. Biochemistry Research International. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1138451
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138451