![](/images/graphics-bg.png)
Protective Effects of Lemon Juice on Alcohol-Induced Liver Injury in Mice
Joint Authors
Zhou, Tong
Zhang, Yu-Jie
Xu, Dong-Ping
Wang, Fang
Zhou, Yue
Zheng, Jie
Li, Ya
Zhang, Jiao-Jiao
Li, Hua-Bin
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-16
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Chronic excessive alcohol consumption (more than 40–80 g/day for males and more than 20–40 g/day for females) could induce serious liver injury.
In this study, effects of lemon juice on chronic alcohol-induced liver injury in mice were evaluated.
The serum biochemical profiles and hepatic lipid peroxidation levels, triacylglycerol (TG) contents, antioxidant enzyme activities, and histopathological changes were examined for evaluating the hepatoprotective effects of lemon juice in mice.
In addition, the in vitro antioxidant capacities of lemon juice were determined.
The results showed that lemon juice significantly inhibited alcohol-induced increase of alanine transaminase (ALT), aspartate transaminase (AST), hepatic TG, and lipid peroxidation levels in a dose-dependent manner.
Histopathological changes induced by alcohol were also remarkably improved by lemon juice treatment.
These findings suggest that lemon juice has protective effects on alcohol-induced liver injury in mice.
The protective effects might be related to the antioxidant capacity of lemon juice because lemon juice showed in vitro antioxidant capacity.
American Psychological Association (APA)
Zhou, Tong& Zhang, Yu-Jie& Xu, Dong-Ping& Wang, Fang& Zhou, Yue& Zheng, Jie…[et al.]. 2017. Protective Effects of Lemon Juice on Alcohol-Induced Liver Injury in Mice. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1138600
Modern Language Association (MLA)
Zhou, Tong…[et al.]. Protective Effects of Lemon Juice on Alcohol-Induced Liver Injury in Mice. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1138600
American Medical Association (AMA)
Zhou, Tong& Zhang, Yu-Jie& Xu, Dong-Ping& Wang, Fang& Zhou, Yue& Zheng, Jie…[et al.]. Protective Effects of Lemon Juice on Alcohol-Induced Liver Injury in Mice. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1138600
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138600