Predictors for High-Risk Carotid Plaque in Asymptomatic Korean Population

Joint Authors

Jang, Chae Won
Kim, Yong Kyun
Kim, Ki-Hong
Chiara, Achangwa
Lee, Moo-Sik
Bae, Jang-Ho

Source

Cardiovascular Therapeutics

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-12-30

Country of Publication

Egypt

No. of Pages

8

Main Topic

Diseases
Medicine

Abstract EN

Aims.

High-risk carotid plaque remains an important risk factor for atherosclerotic cardiovascular disease (ASCVD).

We sought to evaluate the characteristics of carotid plaque and to find out the predictors for high-risk carotid plaque in asymptomatic Koreans.

Methods.

Subjects (n=801) without a history of ASCVD from 12 university hospitals in Korea underwent carotid ultrasound.

The images were standardized at core laboratory.

Morphologic characteristics of plaque were analyzed with laboratory and clinical characteristics.

High-risk carotid plaque features included the highest quartile of carotid plaque score (cPS), irregular plaque surface, and hypoechoic and ulcerated plaque.

Results.

The carotid plaque prevalence was 22.1% (177/801 persons, 293 plaques).

The plaque was increased with age (p<0.001) and conventional ASCVD risk estimator (p<0.001) and the most frequently found in bulb (n=190, 64.8%).

The number of the highest quartile of cPS was 44/177 (24.9%).

Irregular plaque was seen in 20.8% out of total plaque (61/293) and was more frequent in the high-risk 10-year ASCVD risk group than in the low-risk group (36.1% vs.

15.8%, p=0.023).

Hypoechoic and ulcerated plaques were seen in 14.3% (42/293) and 2% (6/293), respectively.

The independent predictors for high-risk plaque were age (β=0.052, p<0.001), HbA1c (β=0.182, p=0.004), male (β=0.118, p=0.006), hypertension (β=0.090, p=0.032), and multiple plaques (OR: 4.810 (two plaques) and 8.621 (three plaques), all p<0.001).

Conclusions.

This study suggests that high-risk carotid plaque was seen in 12.4% (99/801).

The high-risk plaque was associated with diabetes control status reflected by the HbA1c level as well as traditional risk factors in asymptomatic Korean population.

American Psychological Association (APA)

Jang, Chae Won& Kim, Yong Kyun& Kim, Ki-Hong& Chiara, Achangwa& Lee, Moo-Sik& Bae, Jang-Ho. 2020. Predictors for High-Risk Carotid Plaque in Asymptomatic Korean Population. Cardiovascular Therapeutics،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1138614

Modern Language Association (MLA)

Jang, Chae Won…[et al.]. Predictors for High-Risk Carotid Plaque in Asymptomatic Korean Population. Cardiovascular Therapeutics No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1138614

American Medical Association (AMA)

Jang, Chae Won& Kim, Yong Kyun& Kim, Ki-Hong& Chiara, Achangwa& Lee, Moo-Sik& Bae, Jang-Ho. Predictors for High-Risk Carotid Plaque in Asymptomatic Korean Population. Cardiovascular Therapeutics. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1138614

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1138614