Efficacy of Qishen Yiqi Drop Pill for Chronic Heart Failure: An Updated Meta-Analysis of 85 Studies
Joint Authors
Wang, Hao
Li, Lixia
Qing, Xiaochun
Zhang, Shouyan
Li, Shulong
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-23
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Background.
Despite evidence for beneficial effects of Qishen Yiqi Drop Pill (QSYQ) on congestive heart failure, the majority of studies are based on insufficient sample sizes.
The aim of this study was to evaluate the therapeutic effects of QSYQ using a meta-analysis approach.
Methodology/Principal Findings.
All relevant studies published before December 31, 2019, were identified by searches of various databases with key search terms.
In total, 85 studies involving 8,579 participants were included.
The addition of QSYQ to routine Western medicine increased 6-minute walking distance (SMD=2.08, 95% CI: 1.72–2.44, p<0.001), left ventricular ejection fraction (SMD=1.05, 95% CI: 0.87–1.23, p<0.001), and cardiac index (SMD=1.44, 95% CI: 0.92–1.95, p<0.001) and reduced brain natriuretic peptide (SMD=−2.28, 95% CI: -2.81 to -1.76, p<0.001), N-terminal prohormone of brain natriuretic peptide (SMD=−2.49, 95% CI: -3.24 to -1.73, p<0.001), left ventricular end-diastolic dimensions (SMD=−0.92, 95% CI: -1.25 to -0.59, p<0.001), and left ventricular end-systolic dimensions (SMD=−0.55, 95% CI: -0.89 to -0.21, p<0.001).
The results were stable in subgroup analyses and sensitivity analyses.
Conclusions.
Our current meta-analysis indicated that QSYQ combined with Western therapy might be effective in CHF patients.
Further researches are needed to identify which subgroups of CHF patients will benefit most and what kind of combination medicines work best.
American Psychological Association (APA)
Wang, Hao& Li, Lixia& Qing, Xiaochun& Zhang, Shouyan& Li, Shulong. 2020. Efficacy of Qishen Yiqi Drop Pill for Chronic Heart Failure: An Updated Meta-Analysis of 85 Studies. Cardiovascular Therapeutics،Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1138631
Modern Language Association (MLA)
Wang, Hao…[et al.]. Efficacy of Qishen Yiqi Drop Pill for Chronic Heart Failure: An Updated Meta-Analysis of 85 Studies. Cardiovascular Therapeutics No. 2020 (2020), pp.1-14.
https://search.emarefa.net/detail/BIM-1138631
American Medical Association (AMA)
Wang, Hao& Li, Lixia& Qing, Xiaochun& Zhang, Shouyan& Li, Shulong. Efficacy of Qishen Yiqi Drop Pill for Chronic Heart Failure: An Updated Meta-Analysis of 85 Studies. Cardiovascular Therapeutics. 2020. Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1138631
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138631