NPHS2 Mutations: A Closer Look to Latin American Countries
Joint Authors
Belangero, Vera Maria Santoro
Maciel-Guerra, Andréa Trevas
Guerra-Júnior, Gil
Guaragna, Mara Sanches
Lutaif, Anna Cristina G. B.
de Mello, Maricilda Palandi
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Nephrotic syndrome is one of the most common kidney pathologies in childhood, being characterized by proteinuria, edema, and hypoalbuminemia.
In clinical practice, it is divided into two categories based on the response to steroid therapy: steroid-sensitive and steroid resistant.
Inherited impairments of proteins located in the glomerular filtration barrier have been identified as important causes of nephrotic syndrome, with one of these being podocin, coded by NPHS2 gene.
NPHS2 mutations are the most frequent genetic cause of steroid resistant nephrotic syndrome.
The aim of this review is to update the list of NPHS2 mutations reported between June 2013 and February 2017, with a closer look to mutations occurring in Latin American countries.
American Psychological Association (APA)
Guaragna, Mara Sanches& Lutaif, Anna Cristina G. B.& Maciel-Guerra, Andréa Trevas& Belangero, Vera Maria Santoro& Guerra-Júnior, Gil& de Mello, Maricilda Palandi. 2017. NPHS2 Mutations: A Closer Look to Latin American Countries. BioMed Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1138647
Modern Language Association (MLA)
Guaragna, Mara Sanches…[et al.]. NPHS2 Mutations: A Closer Look to Latin American Countries. BioMed Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1138647
American Medical Association (AMA)
Guaragna, Mara Sanches& Lutaif, Anna Cristina G. B.& Maciel-Guerra, Andréa Trevas& Belangero, Vera Maria Santoro& Guerra-Júnior, Gil& de Mello, Maricilda Palandi. NPHS2 Mutations: A Closer Look to Latin American Countries. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1138647
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138647
