![](/images/graphics-bg.png)
Does Chemotherapy for Gynecological Malignancies during Pregnancy Cause Fetal Growth Restriction?
Joint Authors
Abdalla, Nabil
Piórkowski, Robert
Stanirowski, Paweł
Cendrowski, Krzysztof
Sawicki, Włodzimierz
Bizoń, Magdalena
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Cancer and pregnancy rarely coincide.
Gynecological cancers are among the most common malignancies to occur during pregnancy, and chemotherapy with or without surgery is the primary treatment option.
The main concern of administering chemotherapy during pregnancy is congenital malformation, although it can be avoided by delaying treatment until after organogenesis.
The dose, frequency, choice of chemotherapeutic agents, time of treatment commencement, and method of administration can be adjusted to obtain the best maternal treatment outcomes while simultaneously minimizing fetal toxicity.
Use of chemotherapy after the first trimester, while seemingly safe, can cause fetal growth restriction.
However, the exact effect of chemotherapy on such fetal growth restriction has not been fully established; information is scarce owing to the rarity of malignancy occurring during pregnancy, the lack of uniform treatment protocols, different terminologies for defining certain fetal growth abnormalities, the influence of mothers’ preferred options, and ethical issues.
Herein, we present up-to-date findings from the literature regarding the impact of chemotherapy on fetal growth.
American Psychological Association (APA)
Abdalla, Nabil& Bizoń, Magdalena& Piórkowski, Robert& Stanirowski, Paweł& Cendrowski, Krzysztof& Sawicki, Włodzimierz. 2017. Does Chemotherapy for Gynecological Malignancies during Pregnancy Cause Fetal Growth Restriction?. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1138667
Modern Language Association (MLA)
Abdalla, Nabil…[et al.]. Does Chemotherapy for Gynecological Malignancies during Pregnancy Cause Fetal Growth Restriction?. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1138667
American Medical Association (AMA)
Abdalla, Nabil& Bizoń, Magdalena& Piórkowski, Robert& Stanirowski, Paweł& Cendrowski, Krzysztof& Sawicki, Włodzimierz. Does Chemotherapy for Gynecological Malignancies during Pregnancy Cause Fetal Growth Restriction?. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1138667
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138667