Human Gut Microbiota Associated with Obesity in Chinese Children and Adolescents
Joint Authors
Hou, Ya-Ping
He, Qing-Qing
Ouyang, Hai-Mei
Peng, Hai-Shan
Wang, Qun
Li, Jie
Lv, Xiao-Fei
Zheng, Yi-Nan
Li, Shao-Chuan
Liu, Hai-Liang
Yin, Ai-Hua
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
To investigate the gut microbiota differences of obese children compared with the control healthy cohort to result in further understanding of the mechanism of obesity development.
Methods.
We evaluated the 16S rRNA gene, the enterotypes, and quantity of the gut microbiota among obese children and the control cohort and learned the differences of the gut microbiota during the process of weight reduction in obese children.
Results.
In the present study, we learned that the gut microbiota composition was significantly different between obese children and the healthy cohort.
Next we found that functional changes, including the phosphotransferase system, ATP-binding cassette transporters, flagellar assembly, and bacterial chemotaxis were overrepresented, while glycan biosynthesis and metabolism were underrepresented in case samples.
Moreover, we learned that the amount of Bifidobacterium and Lactobacillus increased among the obese children during the process of weight reduction.
Conclusion.
Our results might enrich the research between gut microbiota and obesity and further provide a clinical basis for therapy for obesity.
We recommend that Bifidobacterium and Lactobacillus might be used as indicators of healthy conditions among obese children, as well as a kind of prebiotic and probiotic supplement in the diet to be an auxiliary treatment for obesity.
American Psychological Association (APA)
Hou, Ya-Ping& He, Qing-Qing& Ouyang, Hai-Mei& Peng, Hai-Shan& Wang, Qun& Li, Jie…[et al.]. 2017. Human Gut Microbiota Associated with Obesity in Chinese Children and Adolescents. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1138679
Modern Language Association (MLA)
Hou, Ya-Ping…[et al.]. Human Gut Microbiota Associated with Obesity in Chinese Children and Adolescents. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1138679
American Medical Association (AMA)
Hou, Ya-Ping& He, Qing-Qing& Ouyang, Hai-Mei& Peng, Hai-Shan& Wang, Qun& Li, Jie…[et al.]. Human Gut Microbiota Associated with Obesity in Chinese Children and Adolescents. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1138679
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138679