Radix Bupleuri: A Review of Traditional Uses, Botany, Phytochemistry, Pharmacology, and Toxicology
Joint Authors
Yang, Fude
Dong, Xiaoxv
Yin, Xingbin
Wang, Wenping
You, Longtai
Ni, Jian
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-22, 22 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-16
Country of Publication
Egypt
No. of Pages
22
Main Subjects
Abstract EN
Radix Bupleuri (Chaihu) has been used as a traditional medicine for more than 2000 years in China, Japan, Korea, and other Asian countries.
Phytochemical studies demonstrated that this plant contains essential oils, triterpenoid saponins, polyacetylenes, flavonoids, lignans, fatty acids, and sterols.
Crude extracts and pure compounds isolated from Radix Bupleuri exhibited various biological activities, such as anti-inflammatory, anticancer, antipyretic, antimicrobial, antiviral, hepatoprotective, neuroprotective, and immunomodulatory effects.
However, Radix Bupleuri could also lead to hepatotoxicity, particularly in high doses and with long-term use.
Pharmacokinetic studies have demonstrated that the major bioactive compounds (saikosaponins a, b2, c, and d) were absorbed rapidly in rats after oral administration of the extract of Radix Bupleuri.
This review aims to comprehensively summarize the traditional uses, botany, phytochemistry, pharmacology, toxicology, and pharmacokinetics of Radix Bupleuri reported to date with an emphasis on its biological properties and mechanisms of action.
American Psychological Association (APA)
Yang, Fude& Dong, Xiaoxv& Yin, Xingbin& Wang, Wenping& You, Longtai& Ni, Jian. 2017. Radix Bupleuri: A Review of Traditional Uses, Botany, Phytochemistry, Pharmacology, and Toxicology. BioMed Research International،Vol. 2017, no. 2017, pp.1-22.
https://search.emarefa.net/detail/BIM-1138683
Modern Language Association (MLA)
Yang, Fude…[et al.]. Radix Bupleuri: A Review of Traditional Uses, Botany, Phytochemistry, Pharmacology, and Toxicology. BioMed Research International No. 2017 (2017), pp.1-22.
https://search.emarefa.net/detail/BIM-1138683
American Medical Association (AMA)
Yang, Fude& Dong, Xiaoxv& Yin, Xingbin& Wang, Wenping& You, Longtai& Ni, Jian. Radix Bupleuri: A Review of Traditional Uses, Botany, Phytochemistry, Pharmacology, and Toxicology. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-22.
https://search.emarefa.net/detail/BIM-1138683
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138683