The Influence of Serum Prostate-Specific Antigen on the Accuracy of Magnetic Resonance Imaging Targeted Biopsy versus Saturation Biopsy in Patients with Previous Negative Biopsy
Joint Authors
Chang, Chao-Hsiang
Chiu, Hung-Chieh
Lin, Wei-Ching
Ho, Tzu-Lung
Chang, Han
Chang, Yi-Huei
Huang, Chi-Ping
Wu, Hsi-Chin
Yang, Chi-Rei
Hsieh, Po-Fan
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-11
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
We compared the prostate cancer (PCa) detection rates of targeted biopsy (TB) and saturation biopsy (SB) in patients with previous negative biopsy and the accuracy of TB and SB stratified by different serum prostate-specific antigen (PSA) levels.
Materials and Methods.
Overall 185 patients were enrolled.
In the magnetic resonance imaging (MRI) group, 65 men underwent TB and SB.
In the control group, 120 men underwent SB alone.
The primary outcome was the difference in PCa detection rate between the MRI group and control group.
The secondary outcome was the difference in accuracy between TB and SB in detecting clinically significant PCa by stratifying the patients in the MRI group into those with PSA < 10 ng/ml and PSA ≥ 10 ng/ml.
Results.
The detection rates for overall and clinically significant PCa were higher in the MRI group than in the control group (46.2% versus 20.9% and 43.1% versus 16.7%, both p<0.001).
In the MRI group, the accuracy of TB was higher than SB (94.7% versus 84.2%, p=0.001) for the patients with PSA ≥ 10 ng/mL.
Conclusions.
Combining TB and SB achieved the best cancer detection rate.
The accuracy of TB was better than SB in the patients with serum PSA ≥ 10 ng/mL.
American Psychological Association (APA)
Chang, Chao-Hsiang& Chiu, Hung-Chieh& Lin, Wei-Ching& Ho, Tzu-Lung& Chang, Han& Chang, Yi-Huei…[et al.]. 2017. The Influence of Serum Prostate-Specific Antigen on the Accuracy of Magnetic Resonance Imaging Targeted Biopsy versus Saturation Biopsy in Patients with Previous Negative Biopsy. BioMed Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1138687
Modern Language Association (MLA)
Chang, Chao-Hsiang…[et al.]. The Influence of Serum Prostate-Specific Antigen on the Accuracy of Magnetic Resonance Imaging Targeted Biopsy versus Saturation Biopsy in Patients with Previous Negative Biopsy. BioMed Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1138687
American Medical Association (AMA)
Chang, Chao-Hsiang& Chiu, Hung-Chieh& Lin, Wei-Ching& Ho, Tzu-Lung& Chang, Han& Chang, Yi-Huei…[et al.]. The Influence of Serum Prostate-Specific Antigen on the Accuracy of Magnetic Resonance Imaging Targeted Biopsy versus Saturation Biopsy in Patients with Previous Negative Biopsy. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1138687
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138687