Efficacy of One-Year Treatment with Aflibercept for Diabetic Macular Edema with Practical Protocol
Joint Authors
Oshitari, Toshiyuki
Baba, Takayuki
Arai, Miyuki
Takatsuna, Yoko
Shimizu, Norihiro
Tatsumi, Tomoaki
Kaiho, Tomomi
Yamamoto, Shuichi
Sato, Eiju
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The purpose of this study was to determine the efficacy of one-year treatment of diabetic macular edema (DME) with intravitreal aflibercept (IVA) injections on a practical protocol.
The medical records of 51 eyes of 43 patients who were diagnosed with DME and had received IVA treatments were reviewed.
The best-corrected visual acuity (BCVA) and the central macular thickness (CMT) were measured at the baseline and at 1, 3, 6, and 12 months after the IVA.
The mean number of IVA injections was 3.8±2.4.
The mean BCVA was significantly better and the CMT was thinner after the IVA at all follow-up times (P<0.05).
The BCVA was better in eyes with a serous retinal detachment (SRD) than without a SRD (P<0.01).
There was a significant correlation between the photoreceptor outer segment (PROS) length and BCVA at the baseline and at 12 months after the IVA (P<0.05).
A fewer number of IVA injections significantly improved the BCVA and the CMT in eyes with DME after one-year treatment.
IVA was more effective in the SRD+ group than in the SRD− group.
The PROS length may be a predictive marker for visual outcomes after one-year treatment with IVA for DME (IRB#2272).
American Psychological Association (APA)
Kaiho, Tomomi& Oshitari, Toshiyuki& Tatsumi, Tomoaki& Takatsuna, Yoko& Arai, Miyuki& Shimizu, Norihiro…[et al.]. 2017. Efficacy of One-Year Treatment with Aflibercept for Diabetic Macular Edema with Practical Protocol. BioMed Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1138768
Modern Language Association (MLA)
Kaiho, Tomomi…[et al.]. Efficacy of One-Year Treatment with Aflibercept for Diabetic Macular Edema with Practical Protocol. BioMed Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1138768
American Medical Association (AMA)
Kaiho, Tomomi& Oshitari, Toshiyuki& Tatsumi, Tomoaki& Takatsuna, Yoko& Arai, Miyuki& Shimizu, Norihiro…[et al.]. Efficacy of One-Year Treatment with Aflibercept for Diabetic Macular Edema with Practical Protocol. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1138768
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138768