Relationship between Angiotensin Converting Enzyme, Apelin, and New-Onset Atrial Fibrillation after Off-Pump Coronary Artery Bypass Grafting
Joint Authors
Zhang, Jian
Wang, Huishan
Xu, Shu
Xu, Yin-li
Wu, Hai-bo
Xue, Xiao-dong
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
It has been shown that inflammation and oxidative stress are important factors in postoperative atrial fibrillation (POAF).
Angiotensin converting enzyme (ACE) and apelin have a close relationship with inflammation and oxidative stress.
The effect of ACE and apelin on POAF after off-pump coronary artery bypass grafting (OPCABG) remains a question.
The concentrations of serum ACE, angiotensin II (Ang II), apelin, bradykinin (BK), malondialdehyde (MDA), and C reactive protein (CRP) were measured in the perioperative period of OPCABG.
The levels of serum ACE in the POAF group were higher than in the no POAF group both preoperatively and postoperatively.
Apelin in the POAF group was lower than in the no POAF group.
There was a correlation between serum ACE and apelin.
Postoperatively, CRP and MDA in the POAF group were higher than in the no POAF group; however, there was no difference before the operation.
Preoperative ACE and apelin were both significant and independent risk factors for POAF.
In conclusion, the high ACE and low apelin preoperatively led to CRP and MDA being increased postoperatively, which was probably associated with POAF after OPCABG.
Apelin may be a new predictor for POAF.
American Psychological Association (APA)
Xu, Shu& Zhang, Jian& Xu, Yin-li& Wu, Hai-bo& Xue, Xiao-dong& Wang, Huishan. 2017. Relationship between Angiotensin Converting Enzyme, Apelin, and New-Onset Atrial Fibrillation after Off-Pump Coronary Artery Bypass Grafting. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1138817
Modern Language Association (MLA)
Xu, Shu…[et al.]. Relationship between Angiotensin Converting Enzyme, Apelin, and New-Onset Atrial Fibrillation after Off-Pump Coronary Artery Bypass Grafting. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1138817
American Medical Association (AMA)
Xu, Shu& Zhang, Jian& Xu, Yin-li& Wu, Hai-bo& Xue, Xiao-dong& Wang, Huishan. Relationship between Angiotensin Converting Enzyme, Apelin, and New-Onset Atrial Fibrillation after Off-Pump Coronary Artery Bypass Grafting. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1138817
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1138817