Risk Factors for Rebleeding after Emergency Endoscopic Treatment of Dieulafoy Lesion
Joint Authors
Zhu, Zhenhua
Zhu, Yin
Chen, Youxiang
Lai, Yongkang
Rong, Jianfang
Li, Bimin
Shu, Xu
Liao, Wangdi
Source
Canadian Journal of Gastroenterology and Hepatology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-25
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background and Objective: Dieulafoy lesion is a rare, but life-threatening, cause of gastrointestinal hemorrhage, and endoscopic therapy is the preferred first-line treatment.
The present study aims to analyze the risk factors for rebleeding after endoscopic hemostasis of gastroduodenal Dieulafoy lesion.
Methods.
A retrospective review of patients with Dieulafoy lesion who developed acute gastrointestinal bleeding and were treated primarily with endoscopic therapy from September 2014 to April 2019 was conducted.
Results.
A total of 133 patients with Dieulafoy lesion were included in the present study.
The mean age of these patients was 56.05 ± 16.58 years, and 115 patients were male.
Among these 133 patients, 26 patients developed rebleeding within 30 days of endoscopic therapy.
The 30-day rebleeding rate for pure injection therapy (epinephrine, cyanoacrylate, or lauromacrogol injection alone), nonpure injection therapy (argon plasma coagulation, band ligation, and hemoclip application alone), and combination therapy (combination of any >2 methods) was 45.2%, 12.8%, and 11%, respectively.
In the univariable analysis, endoscopic treatment, prothrombin time, gender, Rockall score, and leukocyte count were the risk factors for rebleeding.
In the multivariable analysis, pure injection endoscopic treatment, white blood cells (>10 × 109/L), and prothrombin time >12 seconds were the independent risk factors for rebleeding.
Conclusion.
Patients who undergo pure injection endoscopic treatment and have a high leukocyte count (>10 × 109/L) or elevated prothrombin time (>12 seconds) have an increased risk of rebleeding within 30 days after endoscopic treatment for gastroduodenal Dieulafoy lesion.
Combined endoscopic treatment is the most effective therapy to prevent rebleeding in gastroduodenal Dieulafoy lesion.
American Psychological Association (APA)
Lai, Yongkang& Rong, Jianfang& Zhu, Zhenhua& Liao, Wangdi& Li, Bimin& Zhu, Yin…[et al.]. 2020. Risk Factors for Rebleeding after Emergency Endoscopic Treatment of Dieulafoy Lesion. Canadian Journal of Gastroenterology and Hepatology،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1139002
Modern Language Association (MLA)
Lai, Yongkang…[et al.]. Risk Factors for Rebleeding after Emergency Endoscopic Treatment of Dieulafoy Lesion. Canadian Journal of Gastroenterology and Hepatology No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1139002
American Medical Association (AMA)
Lai, Yongkang& Rong, Jianfang& Zhu, Zhenhua& Liao, Wangdi& Li, Bimin& Zhu, Yin…[et al.]. Risk Factors for Rebleeding after Emergency Endoscopic Treatment of Dieulafoy Lesion. Canadian Journal of Gastroenterology and Hepatology. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1139002
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139002