Comment on “Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation”

Abstract EN

I read with interest the recent paper by Shen et al.

on the acute presentation of autoimmune hepatitis (AIH) in a Chinese population [1].

In the same period, my colleagues and I published a similar study on a well-characterized cohort of Italian patients [2]; in particular, both we and Shen et al.

used identical selection criteria to define the acute onset of the disease (ALT and AST >X10 upper normal limit and/or total bilirubin >5 mg/dl), and this makes it possible to compare the two experiences.