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Effects of Aspirin and Intrauterine Balloon on Endometrial Repair and Reproductive Prognosis in Patients with Severe Intrauterine Adhesion: A Prospective Cohort Study
Joint Authors
Chen, Yuqing
Liu, Lixiang
Luo, Yuanna
Chen, Minghui
Huan, Yang
Fang, Ruili
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
This study aimed to investigate the effects of estrogen in combination with aspirin and intrauterine balloon on the uterine endometrial repair and reproductive prognosis in patients after surgery for severe intrauterine adhesion (sIUA).
We prospectively recruited 114 patients with sIUA.
Intrauterine device (IUD) was placed and oral estrogen was administered after surgery.
Patients were divided into control group and aspirin group.
In addition, patients in aspirin group were subdivided into nonballoon group and balloon group.
Results showed that, after therapy, the increase in endometrial thickness of aspirin groups was superior to control group (P<0.05).
The scores of intrauterine adhesion and menstruation were significantly improved in balloon group as compared to nonballoon group and control group, and significant differences were also observed between nonballoon group and control group (P<0.05).
Of 97 patients, 44.3% became pregnant after surgery, the live birth rate was 27.8%, and the miscarriage rate was 37.2%, but there were no significant differences among three groups (P>0.05).
Thus, aspirin may promote the uterine endometrial growth and repair after surgery for sIUA, and IUD in combination with intrauterine balloon may reduce the recurrence of intrauterine adhesion, but their effect on the reproductive prognosis is required to be further studied.
American Psychological Association (APA)
Chen, Yuqing& Liu, Lixiang& Luo, Yuanna& Chen, Minghui& Huan, Yang& Fang, Ruili. 2017. Effects of Aspirin and Intrauterine Balloon on Endometrial Repair and Reproductive Prognosis in Patients with Severe Intrauterine Adhesion: A Prospective Cohort Study. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1139121
Modern Language Association (MLA)
Chen, Yuqing…[et al.]. Effects of Aspirin and Intrauterine Balloon on Endometrial Repair and Reproductive Prognosis in Patients with Severe Intrauterine Adhesion: A Prospective Cohort Study. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1139121
American Medical Association (AMA)
Chen, Yuqing& Liu, Lixiang& Luo, Yuanna& Chen, Minghui& Huan, Yang& Fang, Ruili. Effects of Aspirin and Intrauterine Balloon on Endometrial Repair and Reproductive Prognosis in Patients with Severe Intrauterine Adhesion: A Prospective Cohort Study. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1139121
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139121