Analysis of the Salivary Microbiome in Obstructive Sleep Apnea Syndrome Patients
Joint Authors
Jia, Peizeng
Zou, Jianyin
Yin, Shankai
Chen, Feng
Yi, Hongliang
Zhang, Qian
Source
Canadian Journal of Infectious Diseases and Medical Microbiology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-23
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Oral microbiota plays an important role in oral and systemic diseases, while few reports referred to obstructive sleep apnea syndrome (OSAS).
Thus, this study aimed to explore the different salivary microbiome in patients with OSAS and controls.
Materials and Methods.
Saliva was collected from 15 OSAS patients and nine healthy controls, and bacterial genomic DNA was extracted for 16S rRNA amplicon sequencing based on the Illumina platform.
Results.
The alpha and beta diversities were not significantly different between patients with OSAS and controls.
The main phyla in the two groups were Firmicutes, Actinobacteria, Bacteroidetes, Proteobacteria, and Fusobacteria, which accounted for 95% of the abundance.
The main genera were Streptococcus, Rothia, Actinomyces, Prevotella, and Neisseria.
Based on the genus and operational taxonomic units, Peptostreptococcus, Alloprevotella, and Granulicatella were enriched in controls, while only Scardovia species were significantly more abundant in patients with OSAS.
Conclusions.
There was no significant difference in the relative abundance of bacteria between OSAS and controls.
So, further studies will need to focus on the metagenome of bacteria in OSAS patients.
American Psychological Association (APA)
Jia, Peizeng& Zou, Jianyin& Yin, Shankai& Chen, Feng& Yi, Hongliang& Zhang, Qian. 2020. Analysis of the Salivary Microbiome in Obstructive Sleep Apnea Syndrome Patients. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1139159
Modern Language Association (MLA)
Jia, Peizeng…[et al.]. Analysis of the Salivary Microbiome in Obstructive Sleep Apnea Syndrome Patients. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1139159
American Medical Association (AMA)
Jia, Peizeng& Zou, Jianyin& Yin, Shankai& Chen, Feng& Yi, Hongliang& Zhang, Qian. Analysis of the Salivary Microbiome in Obstructive Sleep Apnea Syndrome Patients. Canadian Journal of Infectious Diseases and Medical Microbiology. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1139159
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139159