Microbial Predominance and Antimicrobial Resistance in a Tertiary Hospital in Northwest China: A Six-Year Retrospective Study of Outpatients and Patients Visiting the Emergency Department
Joint Authors
Li, Yali
Li, Wen
Wang, Caifeng
Gao, Juanjuan
Zhang, Dancheng
Lei, Jine
Li, Fang
Source
Canadian Journal of Infectious Diseases and Medical Microbiology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
With the wide use of antibiotics, antimicrobial resistance becomes a serious issue.
Timely understanding of microbial pathogen profiles and the change of antimicrobial resistance provide an important guidance for effective and optimized use of antibiotics in local healthcare systems.
The aim was to investigate the characteristics of microbial species and their antimicrobial resistances in a tertiary hospital with an Emergency Department and outpatient clinics for a period of six years.
Methodology.
A retrospective study was conducted using the HIS database of a tertiary hospital between 2013 and 2018.
Antimicrobial susceptibility was tested by automated systems and/or the Kirby–Bauer disc diffusion method.
The data were analyzed using the WHONET 5.6 software.
The Cochran-Armitage test was used to study the trends over the period of research.
Results.
In a total of 19,028 specimens submitted for microbial tests during the period from 49 units of the hospital, only the samples from the Emergency Department and Kidney Transplantation Clinic showed an annually significant increase (P<0.001).
More than 200 species with 46.4% gram-positive cocci and 45.3% gram-negative bacilli were identified in the 3,849 nonrepetitive isolates.
The methicillin-resistant S.
aureus and S.
epidermidis rates were 25.1% and 74.6%, respectively.
60.9% E.
coli and 33.5% K.
pneumonia samples carried extended-spectrum-β-lactamase.
All Staphylococci and Enterococci samples were not resistant to linezolid, vancomycin, and tigecycline.
In addition, only 0.01% E.
coli, 1.1% K.
pneumonia, and 18.7% P.
aeruginosa isolates showed resistance to carbapenems.
Conclusions.
Vancomycin, linezolid and tigecycline were the most effective antibiotics for outpatients with gram-positive infection.
Carbapenems were the most effective antibiotics for gram-negative infection.
There was no significant annual increase of common multidrug resistances.
American Psychological Association (APA)
Wang, Caifeng& Li, Wen& Gao, Juanjuan& Zhang, Dancheng& Li, Yali& Li, Fang…[et al.]. 2020. Microbial Predominance and Antimicrobial Resistance in a Tertiary Hospital in Northwest China: A Six-Year Retrospective Study of Outpatients and Patients Visiting the Emergency Department. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1139193
Modern Language Association (MLA)
Wang, Caifeng…[et al.]. Microbial Predominance and Antimicrobial Resistance in a Tertiary Hospital in Northwest China: A Six-Year Retrospective Study of Outpatients and Patients Visiting the Emergency Department. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1139193
American Medical Association (AMA)
Wang, Caifeng& Li, Wen& Gao, Juanjuan& Zhang, Dancheng& Li, Yali& Li, Fang…[et al.]. Microbial Predominance and Antimicrobial Resistance in a Tertiary Hospital in Northwest China: A Six-Year Retrospective Study of Outpatients and Patients Visiting the Emergency Department. Canadian Journal of Infectious Diseases and Medical Microbiology. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1139193
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139193