A Clinic Trial Evaluating the Effects of Aloe Vera Fermentation Gel on Recurrent Aphthous Stomatitis
Joint Authors
Wei, Jing
Wei, Kehong
Lu, Jiachen
Hu, Xiaojing
Chen, Tingtao
Shi, Yan
Source
Canadian Journal of Infectious Diseases and Medical Microbiology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-07
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Recurrent aphthous stomatitis (RAS) is the most common disorder in the oral mucosa that affects the daily quality of life of patients, and there is currently no specific treatment.
In the present study, we developed aloe vera fermentation gel under the action of probiotics on aloe vera.
In total, 35 patients with the history of aphthous stomatitis were enrolled to explore the potential benefits of aloe vera fermentation gel to treat RAS, and the healing-promotion effects were recorded and compared; microbial compositions in different groups were tested by high-throughput sequencing.
Our results indicated that the duration of healing time of the aloe group showed potentially better effects because of the higher proportion of 4–6 day healing time (35% vs.
20%) and lower proportion of 7–10 day healing time (65% vs.
80%) compared with that of the chitosan group.
Also, the use of aloe vera fermentation gel could return oral bacteria to normal levels and reduce the abundance of harmful oral bacteria including Actinomyces, Granulicatella, and Peptostreptococcus.
These results suggest that aloe vera fermentation gel has the ability to treat patients with RAS and has positive prospects in clinical applications.
American Psychological Association (APA)
Shi, Yan& Wei, Kehong& Lu, Jiachen& Wei, Jing& Hu, Xiaojing& Chen, Tingtao. 2020. A Clinic Trial Evaluating the Effects of Aloe Vera Fermentation Gel on Recurrent Aphthous Stomatitis. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1139198
Modern Language Association (MLA)
Shi, Yan…[et al.]. A Clinic Trial Evaluating the Effects of Aloe Vera Fermentation Gel on Recurrent Aphthous Stomatitis. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1139198
American Medical Association (AMA)
Shi, Yan& Wei, Kehong& Lu, Jiachen& Wei, Jing& Hu, Xiaojing& Chen, Tingtao. A Clinic Trial Evaluating the Effects of Aloe Vera Fermentation Gel on Recurrent Aphthous Stomatitis. Canadian Journal of Infectious Diseases and Medical Microbiology. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1139198
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139198