Effect of Regular Aerobic Activity in Young Healthy Athletes on Profile of Endothelial Function and Platelet Activity
Joint Authors
Szuba, Andrzej
Skomro, Robert
Szahidewicz-Krupska, E.
Mazur, G.
Doroszko, A.
Derkacz, Arkadiusz
Dobrowolski, Piotr
Radziwon, Aneta
Podgórska, Katarzyna
Jasiczek, Jakub
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The aim of the study was to assess the impact of regular professional sports activity on the endothelial and platelet function in young men.
The studied group were 79 young men (18–40 y, 25 athletes and 54 without any regular physical activity).
The nitric oxide (NO) metabolic pathway intermediates, oxidative stress markers, mediators of inflammation, and platelet aggregation were measured.
Flow mediated dilation (FMD) was studied before and after intravenous 16,0 g L-arginine infusion, which was repeated after oral administration of acetylsalicylic acid (ASA-75 mg/day) for 4 days.
Both groups had similar demographic characteristics.
In the athletes, there was significantly higher hsCRP level, better serum lipid profile, and lower pulse pressure.
Greater baseline FMD in athletes and in response to L-arginine disappeared following ASA treatment.
There were no differences in the levels of the NO pathway metabolites.
The control group was characterized by higher PAI-1 following ASA treatment and sICAM-1 both at baseline and after ASA, but no differences in MDA and 6-keto-PGF-1 alpha and platelet aggregation were noted.
Regular professional physical activity modulates endothelial but not platelet function and may thus exert an effect on overall cardiovascular risk.
American Psychological Association (APA)
Podgórska, Katarzyna& Derkacz, Arkadiusz& Szahidewicz-Krupska, E.& Jasiczek, Jakub& Dobrowolski, Piotr& Radziwon, Aneta…[et al.]. 2017. Effect of Regular Aerobic Activity in Young Healthy Athletes on Profile of Endothelial Function and Platelet Activity. BioMed Research International،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1139232
Modern Language Association (MLA)
Podgórska, Katarzyna…[et al.]. Effect of Regular Aerobic Activity in Young Healthy Athletes on Profile of Endothelial Function and Platelet Activity. BioMed Research International No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1139232
American Medical Association (AMA)
Podgórska, Katarzyna& Derkacz, Arkadiusz& Szahidewicz-Krupska, E.& Jasiczek, Jakub& Dobrowolski, Piotr& Radziwon, Aneta…[et al.]. Effect of Regular Aerobic Activity in Young Healthy Athletes on Profile of Endothelial Function and Platelet Activity. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1139232
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139232