The Use of Carbon Quantum Dot as Alternative of Stannous Chloride Application in Radiopharmaceutical Kits
Joint Authors
Ghoreishi, Seyedeh Masoumeh
Najdian, Atena
Yadegari, Sina
Seyedhamzeh, Mohammad
Etemadzade, Maziyar
Mirzaei, Mehdi
Hadadian, Shahin
Alikhani, Zahra
Ardestani, Mehdi Shafiee
Source
Contrast Media & Molecular Imaging
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-06
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Even today, technetium-99m is a radionuclide choice for diagnostic in nuclear medicine.
The unique chemical and physical properties of technetium-99m make it suitable as an available radionuclide in many centers.
In this study, we examined the potential of CQD as a reducing agent in the MDP kit.
Citric acid-derived CQD was synthesized and confirmed by FT-IR, TEM, UV-Vis, XPS, and surface analysis.
No cytotoxicity was observed by the MTT assay.
They were reducing properties of the CQD confirmed by fluorescence microscopy.
The MDP kit is prepared by evaluating different parameters that affect the radiolabeling yield, including ligand, time, and CQD.
The optimum amount of each parameter is obtained by Box–Behnken software.
Finally, fluorescent spectroscopy, SPECT imaging, and biodistribution study showed that CQD reduces technetium-99m.
Accumulation of radiotracer in the femur showed that CQD could be used in a radiopharmaceutical kit.
American Psychological Association (APA)
Ghoreishi, Seyedeh Masoumeh& Najdian, Atena& Yadegari, Sina& Seyedhamzeh, Mohammad& Etemadzade, Maziyar& Mirzaei, Mehdi…[et al.]. 2020. The Use of Carbon Quantum Dot as Alternative of Stannous Chloride Application in Radiopharmaceutical Kits. Contrast Media & Molecular Imaging،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1139251
Modern Language Association (MLA)
Ghoreishi, Seyedeh Masoumeh…[et al.]. The Use of Carbon Quantum Dot as Alternative of Stannous Chloride Application in Radiopharmaceutical Kits. Contrast Media & Molecular Imaging No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1139251
American Medical Association (AMA)
Ghoreishi, Seyedeh Masoumeh& Najdian, Atena& Yadegari, Sina& Seyedhamzeh, Mohammad& Etemadzade, Maziyar& Mirzaei, Mehdi…[et al.]. The Use of Carbon Quantum Dot as Alternative of Stannous Chloride Application in Radiopharmaceutical Kits. Contrast Media & Molecular Imaging. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1139251
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139251