Amphiphilic Polymer-Modified Uniform CuFeSe2 Nanoparticles for CTMR Dual-Modal Imaging

Abstract EN

Recently, magnetic photothermal nanomaterials have attracted much attention in the diagnosis and treatment of cancer.

In this study, we developed the ultrasmall magnetic CuFeSe2 nanoparticles for CT/MR dual-modal imaging.

By controlling the reaction time and condition, CuFeSe2 nanoparticles were synthesized by a simple directly aqueous method.

After modification with copolymer methoxy polyethylene glycol-polycaprolactone (MPEG-PCL), the obtained MPEG-PCL@CuFeSe2 nanoparticles showed excellent water solubility, colloidal stability, and biocompatibility.

In addition, they also exhibited superparamagnetism and X-ray’s characteristics.

For these properties, they will become ideal nanomaterials for CT/MR dual-modal imaging.