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Diagnostic Performance of PET or PETCT with Different Radiotracers in Patients with Suspicious Lung Cancer or Pleural Tumours according to Published Meta-Analyses
Joint Authors
Treglia, Giorgio
Lococo, Filippo
Muoio, Barbara
Chiappetta, Marco
Nachira, Dania
Petracca Ciavarella, Leonardo
Margaritora, Stefano
Source
Contrast Media & Molecular Imaging
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-25
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
Several meta-analyses have reported data about the diagnostic performance of positron emission tomography or positron emission tomography/computed tomography (PET or PET/CT) with different radiotracers in patients with suspicious lung cancer (LC) or pleural tumours (PT).
This review article aims at providing an overview on the recent evidence-based data in this setting.
Methods.
A comprehensive literature search of meta-analyses published in PubMed/MEDLINE and Cochrane Library database from January 2010 through March 2020 about the diagnostic performance of PET or PET/CT with different radiotracers in patients with suspicious LC or PT was performed.
This combination of keywords was used: (A) “PET” OR “positron emission tomography” AND (B) “lung” OR “pulmonary” OR “pleur∗” AND (C) meta-analysis.
Only meta-analyses on PET or PET/CT in patients with suspicious LC or PT were selected.
Results.
We have summarized the diagnostic performance of PET or PET/CT with fluorine-18 fluorodeoxyglucose (18F-FDG) and other radiotracers taking into account 17 meta-analyses.
Evidence-based data demonstrated a good diagnostic performance of 18F-FDG PET or PET/CT for the characterization of solitary pulmonary nodules (SPNs) or pleural lesions with overall higher sensitivity than specificity.
Evidence-based data do not support the routine use of dual time point (DTP) 18F-FDG PET/CT or fluorine-18 fluorothymidine (18F-FLT) PET/CT in the differential diagnosis of SPNs.
Even if 18F-FDG PET/CT has high sensitivity and specificity as a selective screening modality for LC, its role in this setting remains unknown.
Conclusions.
Evidence-based data about the diagnostic performance of PET/CT with different radiotracers for suspicious LC or PT are increasing, with good diagnostic performance of 18F-FDG PET/CT.
More prospective multicenter studies and cost-effectiveness analyses are warranted.
American Psychological Association (APA)
Lococo, Filippo& Muoio, Barbara& Chiappetta, Marco& Nachira, Dania& Petracca Ciavarella, Leonardo& Margaritora, Stefano…[et al.]. 2020. Diagnostic Performance of PET or PETCT with Different Radiotracers in Patients with Suspicious Lung Cancer or Pleural Tumours according to Published Meta-Analyses. Contrast Media & Molecular Imaging،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1139258
Modern Language Association (MLA)
Lococo, Filippo…[et al.]. Diagnostic Performance of PET or PETCT with Different Radiotracers in Patients with Suspicious Lung Cancer or Pleural Tumours according to Published Meta-Analyses. Contrast Media & Molecular Imaging No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1139258
American Medical Association (AMA)
Lococo, Filippo& Muoio, Barbara& Chiappetta, Marco& Nachira, Dania& Petracca Ciavarella, Leonardo& Margaritora, Stefano…[et al.]. Diagnostic Performance of PET or PETCT with Different Radiotracers in Patients with Suspicious Lung Cancer or Pleural Tumours according to Published Meta-Analyses. Contrast Media & Molecular Imaging. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1139258
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139258