Is 18F-FDG PETCT an Accurate Way to Detect Lymph Node Metastasis in Colorectal Cancer: A Systematic Review and Meta-Analysis

Abstract EN

Aims.

The purpose of this study was to assess the diagnostic value of 18F-fluorodeoxy-glucose positron emission tomography/computed tomography (FDG PET/CT) for detection of lymph node (LN) metastasis of colorectal cancer.

Material and Methods.

A computerized search was performed to determine the relevant articles, published before October 2019.

Stata Statistical Software, version 15.0, and Meta-Disc (version 1.4) were used for the meta-analysis.

Results.

the sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio were 0.65, 0.75, 4.57, and 0.37 respectively.

Studies that used SUVmax cut-off value (≤2.5) demonstrated the best accuracy.

Conclusion.

18F-FDG PET/CT shows a low sensitivity and high specificity for detecting the metastasis of LNs in patients with newly diagnosed colorectal cancer.