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Changes in Somatostatin-Like Immunoreactivity in the Sympathetic Neurons Projecting to the Prepyloric Area of the Porcine Stomach Induced by Selected Pathological Conditions
Joint Authors
Palus, Katarzyna
Całka, Jarosław
Bulc, Michał
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-02
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The aim of the present study was to define changes in the expression of somatostatin (SOM) in the sympathetic perikarya innervating the porcine stomach prepyloric area during acetylsalicylic-acid-induced gastritis (ASA) and experimentally induced hyperacidity (HCL) and following partial stomach resection (RES).
On day 1, the stomachs were injected with neuronal retrograde tracer Fast Blue (FB).
Animals in the ASA group were given acetylsalicylic acid orally for 21 days.
On the 22nd day after FB injection, partial stomach resection was performed in RES animals.
On day 23, HCL animals were intragastrically given 5 ml/kg of body weight of a 0.25 M aqueous solution of hydrochloric acid.
On day 28, all pigs were euthanized.
Then, 14-μm thick cryostat sections of the coeliac-superior mesenteric ganglion (CSMG) complexes were processed for routine double-labelling immunofluorescence.
All pathological conditions studied resulted in upregulation of SOM-like (SOM-LI) immunoreactivity (from 14.97±1.57% in control group to 33.72±4.39% in the ASA group, to 39.02±3.65% in the RES group, and to 29.63±0.85% in the HCL group).
The present studies showed that altered expression of SOM occurs in sympathetic neurons supplying the prepyloric area of the porcine stomach during adaptation to various pathological insults.
American Psychological Association (APA)
Palus, Katarzyna& Bulc, Michał& Całka, Jarosław. 2017. Changes in Somatostatin-Like Immunoreactivity in the Sympathetic Neurons Projecting to the Prepyloric Area of the Porcine Stomach Induced by Selected Pathological Conditions. BioMed Research International،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1139310
Modern Language Association (MLA)
Palus, Katarzyna…[et al.]. Changes in Somatostatin-Like Immunoreactivity in the Sympathetic Neurons Projecting to the Prepyloric Area of the Porcine Stomach Induced by Selected Pathological Conditions. BioMed Research International No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1139310
American Medical Association (AMA)
Palus, Katarzyna& Bulc, Michał& Całka, Jarosław. Changes in Somatostatin-Like Immunoreactivity in the Sympathetic Neurons Projecting to the Prepyloric Area of the Porcine Stomach Induced by Selected Pathological Conditions. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1139310
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139310