Virtual FFR Quantified with a Generalized Flow Model Using Windkessel Boundary Conditions
Joint Authors
Chahour, Keltoum
Aboulaich, Rajae
Habbal, Abderrahmane
Zemzemi, Nejib
Abdelkhirane, Chérif
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-21
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Fractional flow reserve (FFR) has proved its efficiency in improving patient diagnosis.
In this paper, we consider a 2D reconstructed left coronary tree with two artificial lesions of different degrees.
We use a generalized fluid model with a Carreau law and use a coupled multidomain method to implement Windkessel boundary conditions at the outlets.
We introduce our methodology to quantify the virtual FFR and conduct several numerical experiments.
We compare FFR results from the Navier–Stokes model versus generalized flow model and for Windkessel versus traction-free outlet boundary conditions or mixed outlet boundary conditions.
We also investigate some sources of uncertainty that the FFR index might encounter during the invasive procedure, in particular, the arbitrary position of the distal sensor.
The computational FFR results show that the degree of stenosis is not enough to classify a lesion, while there is a good agreement between the Navier–Stokes model and the non-Newtonian flow model adopted in classifying coronary lesions.
Furthermore, we highlight that the lack of standardization while making FFR measurement might be misleading regarding the significance of stenosis.
American Psychological Association (APA)
Chahour, Keltoum& Aboulaich, Rajae& Habbal, Abderrahmane& Zemzemi, Nejib& Abdelkhirane, Chérif. 2020. Virtual FFR Quantified with a Generalized Flow Model Using Windkessel Boundary Conditions. Computational and Mathematical Methods in Medicine،Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1139416
Modern Language Association (MLA)
Chahour, Keltoum…[et al.]. Virtual FFR Quantified with a Generalized Flow Model Using Windkessel Boundary Conditions. Computational and Mathematical Methods in Medicine No. 2020 (2020), pp.1-14.
https://search.emarefa.net/detail/BIM-1139416
American Medical Association (AMA)
Chahour, Keltoum& Aboulaich, Rajae& Habbal, Abderrahmane& Zemzemi, Nejib& Abdelkhirane, Chérif. Virtual FFR Quantified with a Generalized Flow Model Using Windkessel Boundary Conditions. Computational and Mathematical Methods in Medicine. 2020. Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1139416
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139416