![](/images/graphics-bg.png)
Preparation of P3HB4HB(Gelatin + PVA) Composite Scaffolds by Coaxial Electrospinning and Its Biocompatibility Evaluation
Joint Authors
Ye, Chuan
Ma, Min-Xian
Liu, Qin
Grottkau, Brian
Guo, Bing
Song, Yu-Feng
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-19
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
This study was conducted to prepare coaxial electrospun scaffolds of P3HB4HB/(gelatin + PVA) with various concentration ratios with P3HB4HB as the core solution and gelatin + PVA mixture as the shell solution; the mass ratios of gelatin and PVA in each 10 mL shell mixture were 0.6 g : 0.2 g (Group A), 0.4 g : 0.4 g (Group B), and 0.2 g : 0.6 g (Group C).
The results showed that the pore size, porosity, and cell proliferation rate of Group C were better than those of Groups A and B.
The ascending order of the tensile strength and modulus of elasticity was Group A < Group B < Group C.
The surface roughness was Group C > Group B > Group A.
The osteogenic and chondrogenic-specific staining showed that Group C was stronger than Groups A and B.
This study demonstrates that when the mass ratio of gelatin : PVA was 0.2 g : 0.6 g, a P3HB4HB/(gelatin + PVA) composite scaffold with a core-shell structure can be prepared, and the scaffold has good biocompatibility that it may be an ideal scaffold for tissue engineering.
American Psychological Association (APA)
Ma, Min-Xian& Liu, Qin& Ye, Chuan& Grottkau, Brian& Guo, Bing& Song, Yu-Feng. 2017. Preparation of P3HB4HB(Gelatin + PVA) Composite Scaffolds by Coaxial Electrospinning and Its Biocompatibility Evaluation. BioMed Research International،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1139423
Modern Language Association (MLA)
Ma, Min-Xian…[et al.]. Preparation of P3HB4HB(Gelatin + PVA) Composite Scaffolds by Coaxial Electrospinning and Its Biocompatibility Evaluation. BioMed Research International No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1139423
American Medical Association (AMA)
Ma, Min-Xian& Liu, Qin& Ye, Chuan& Grottkau, Brian& Guo, Bing& Song, Yu-Feng. Preparation of P3HB4HB(Gelatin + PVA) Composite Scaffolds by Coaxial Electrospinning and Its Biocompatibility Evaluation. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1139423
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139423