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3D Simulation Analysis of Central Shunt in Patient-Specific Hemodynamics: Effects of Varying Degree of Pulmonary Artery Stenosis and Shunt Diameters
Joint Authors
Zhang, Neichuan
Yuan, Haiyun
Chen, Xiangyu
Liu, Jiawei
Jian, Qifei
Huang, Meiping
Zhou, Chengbin
Zhuang, Jian
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-14
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The objective of this study was to compare the effects of different shunt diameters and pulmonary artery (PA) stenosis grades on the hemodynamics of central shunts to determine an optimal surgical plan and improve the long-term outcomes of the operation.
A 3D anatomical model was reconstructed based on the patient’s clinical CT data.
3D computational fluid dynamics models were built with varying degrees of stenosis (the stenosis ratio α was represented by the ratio of blood flow through the main pulmonary artery to cardiac output, ranging from 0 to 30%; the smaller the value of α, the more severe the pulmonary artery stenosis) and varying shunt diameters (3, 3.5, 4, 4.5, and 5 mm).
Our results show that the asymmetry of pulmonary artery flow increased with increasing shunt diameter and α, which will be more conducive to the development of the left pulmonary artery.
Additionally, the pulmonary-to-systemic flow ratio (QP/QS) increases with the shunt diameter and α, and all the values exceed 1.
When the shunt diameter is 3 mm and α = 0%, QP/QS reaches the minimum value of 1.01, and the oxygen delivery reaches the maximum value of 205.19 ml/min.
However, increasing shunt diameter and α is beneficial to reduced power loss and smoother PA flow.
In short, for patients with severe PA stenosis (α is small), a larger-diameter shunt may be preferred.
Conversely, when the degree of PA stenosis is moderate, a smaller shunt diameter can be considered.
American Psychological Association (APA)
Liu, Jiawei& Yuan, Haiyun& Zhang, Neichuan& Chen, Xiangyu& Zhou, Chengbin& Huang, Meiping…[et al.]. 2020. 3D Simulation Analysis of Central Shunt in Patient-Specific Hemodynamics: Effects of Varying Degree of Pulmonary Artery Stenosis and Shunt Diameters. Computational and Mathematical Methods in Medicine،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1139449
Modern Language Association (MLA)
Liu, Jiawei…[et al.]. 3D Simulation Analysis of Central Shunt in Patient-Specific Hemodynamics: Effects of Varying Degree of Pulmonary Artery Stenosis and Shunt Diameters. Computational and Mathematical Methods in Medicine No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1139449
American Medical Association (AMA)
Liu, Jiawei& Yuan, Haiyun& Zhang, Neichuan& Chen, Xiangyu& Zhou, Chengbin& Huang, Meiping…[et al.]. 3D Simulation Analysis of Central Shunt in Patient-Specific Hemodynamics: Effects of Varying Degree of Pulmonary Artery Stenosis and Shunt Diameters. Computational and Mathematical Methods in Medicine. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1139449
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139449