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The Impact of Age on Clinical Outcomes of Coronary Artery Bypass Grafting: Long-Term Results of a Real-World Registry
Joint Authors
Nicolini, Francesco
Vezzani, Antonella
Fortuna, Daniela
Contini, Giovanni Andrea
Pacini, Davide
Gabbieri, Davide
Zussa, Claudio
De Palma, Rossana
Gherli, Tiziano
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-20
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The aim of this retrospective multicenter registry study was to investigate age-dependent trends in mortality, long-term survival, and comorbidity over time in patients who underwent isolated CABG from 2003 to 2015.
The percentage of patients < 60 years of age was 18.9%.
Female sex, chronic pulmonary disease, extracardiac arteriopathy, and neurologic dysfunction disease were significantly less frequent in this younger population.
The prevalence of BMI ≥ 30, previous myocardial infarction, preoperative severe depressed left ventricular ejection fraction, and history of previous PCI were significantly higher in this population.
After PS matching, at 5 years, patients < 60 years of age reported significantly lower overall mortality (p<0.0001), cardiac-related mortality (p<0.0001), incidence of acute myocardial infarction (p=0.01), and stroke rates (p<0.0001).
Patients < 60 years required repeated revascularization more frequently than older patients (p=0.05).
Patients < 60 who underwent CABG had a lower risk of adverse outcomes than older patients.
Patients < 60 have a different clinical pattern of presentation of CAD in comparison with more elderly patients.
These issues require focused attention in order to design and improve preventive strategies aiming to reduce the impact of specific cardiovascular risk factors for younger patients, such as diet, lifestyle, and weight control.
American Psychological Association (APA)
Nicolini, Francesco& Fortuna, Daniela& Contini, Giovanni Andrea& Pacini, Davide& Gabbieri, Davide& Zussa, Claudio…[et al.]. 2017. The Impact of Age on Clinical Outcomes of Coronary Artery Bypass Grafting: Long-Term Results of a Real-World Registry. BioMed Research International،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1139732
Modern Language Association (MLA)
Nicolini, Francesco…[et al.]. The Impact of Age on Clinical Outcomes of Coronary Artery Bypass Grafting: Long-Term Results of a Real-World Registry. BioMed Research International No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1139732
American Medical Association (AMA)
Nicolini, Francesco& Fortuna, Daniela& Contini, Giovanni Andrea& Pacini, Davide& Gabbieri, Davide& Zussa, Claudio…[et al.]. The Impact of Age on Clinical Outcomes of Coronary Artery Bypass Grafting: Long-Term Results of a Real-World Registry. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1139732
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139732