Bone Marrow Metastasis Is an Early Stage of Bone Metastasis in Breast Cancer Detected Clinically by F18-FDG-PETCT Imaging
Author
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
To determine the value of 18F-FDG PET/CT in detection of bone marrow (BM) metastasis in breast cancer which is considered an early stage of bone metastasis.
Patients and Methods.
Retrospectively, breast cancer patients with bone metastasis were included.
BM metastasis was considered if the lesion was PET positive/CT occult while bone metastasis was considered if the lesion was PET positive/ CT positive.
BM metastases were observed sequentially on F18-FDG PET/CT.
Results.
We included 35 patients.
Eighteen patients (51%) had BM metastases in addition to other bone metastases.
BM metastases comprised 24% of all lesions.
Posttreatment scan was performed on 26/35 patients.
Twenty-three percent of BM metastases had resolved completely without causing bone destruction after treatment.
Sixty-five percent of BM metastases had converted into bone metastases after treatment.
Twelve percent of BM metastases had persisted after treatment.
Conclusion.
This retrospective study showed clinically by 18F-FDG PET/CT imaging that BM metastasis is an early stage of bone metastasis in breast cancer.
Interestingly, 18F-FDG-PET/CT showed that early eradication of individual BM metastasis by systemic treatment precluded development of bone metastasis.
However, more research is needed to study the impact of an early diagnosis of BM metastases on treatment outcome.
American Psychological Association (APA)
Al-Muqbel, Kusai M.. 2017. Bone Marrow Metastasis Is an Early Stage of Bone Metastasis in Breast Cancer Detected Clinically by F18-FDG-PETCT Imaging. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1139739
Modern Language Association (MLA)
Al-Muqbel, Kusai M.. Bone Marrow Metastasis Is an Early Stage of Bone Metastasis in Breast Cancer Detected Clinically by F18-FDG-PETCT Imaging. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1139739
American Medical Association (AMA)
Al-Muqbel, Kusai M.. Bone Marrow Metastasis Is an Early Stage of Bone Metastasis in Breast Cancer Detected Clinically by F18-FDG-PETCT Imaging. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1139739
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139739