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How to Use CA-125 More Effectively in the Diagnosis of Deep Endometriosis
Joint Authors
Evangelista, Alessandra Viviane
Oliveira, Marco Aurelio Pinho
Raymundo, Thiers Soares
Soares, Leila Cristina
Pereira, Thiago Rodrigues Dantas
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Deep infiltrative endometriosis (DIE) is a severe form of the disease.
The median time interval from the onset of symptoms to diagnosis of endometriosis is around 8 years.
In this prospective study patients were divided into two groups: cases (34 DIE patients) and control (20 tubal ligation patients).
The main objective of this study was to evaluate the performance of CA-125 measurement in the menstrual and midcycle phases of the cycle, as well as the difference in its levels between the two phases, for the early diagnosis of DIE.
Area Under the Curve (AUC) of CA-125 in menstrual phase and of the difference between menstrual and midcycle phases had the best performance (both with AUC = 0.96), followed by CA-125 in the midcycle (AUC = 0.89).
The ratio between menstrual and midcycle phases had the worst performance.
CA-125 may be useful for the diagnosis of deep endometriosis, especially when both are collected during menstruation and in midcycle.
These may help to decrease the long interval until the definitive diagnosis of DIE.
Multicentric studies with larger samples should be performed to better evaluate the cost-effectiveness of measuring CA-125 in two different phases of the menstrual cycle.
American Psychological Association (APA)
Oliveira, Marco Aurelio Pinho& Raymundo, Thiers Soares& Soares, Leila Cristina& Pereira, Thiago Rodrigues Dantas& Evangelista, Alessandra Viviane. 2017. How to Use CA-125 More Effectively in the Diagnosis of Deep Endometriosis. BioMed Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1139742
Modern Language Association (MLA)
Oliveira, Marco Aurelio Pinho…[et al.]. How to Use CA-125 More Effectively in the Diagnosis of Deep Endometriosis. BioMed Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1139742
American Medical Association (AMA)
Oliveira, Marco Aurelio Pinho& Raymundo, Thiers Soares& Soares, Leila Cristina& Pereira, Thiago Rodrigues Dantas& Evangelista, Alessandra Viviane. How to Use CA-125 More Effectively in the Diagnosis of Deep Endometriosis. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1139742
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139742