The Incorporation of Strontium in a Sodium Alginate Coating on Titanium Surfaces for Improved Biological Properties
Joint Authors
Liu, Yunde
Zhu, S. L.
Cui, Z. D.
Yang, X. J.
Liang, Y. Q.
Li, Z. Y.
Yuan, Ning
Jia, Lili
Geng, Zhen
Wang, Renfeng
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-03
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Orthopedic implant failure is mainly attributed to the poor bonding of the implant to bone tissue.
An effective approach to minimize the implant failure would be modifying the surface of the implant.
Strontium (Sr) can stimulate the proliferation and differentiation of osteoblasts and reduce the activity of osteoclasts.
In this study, a titanium (Ti) surface was successively functionalized by covalently grafting dopamine, sodium alginate (SA), and Sr2+ via the electrostatic immobilization method.
The as-prepared coatings on the Ti surface were characterized by using scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FT-IR), and contact angle.
The results indicated that the Sr-incorporated coatings were successfully prepared and that Sr distributed uniformly on the surface.
A long-lasting and sustained Sr release had been observed in Sr2+ release studies.
The Ti/DOPA/SA/Sr exhibited little cytotoxicity and a robust effect of Sr incorporation on the adhesion and spreading of MG63 cells.
The proliferation and alkaline phosphatase (ALP) activity of MG63 cells were enhanced by immobilizing Sr2+ on the SA-grafted Ti.
The Sr-containing coatings, which displayed excellent biocompatibility and osteogenic activity, may provide a promising solution for promoting the tissue integration of implants.
American Psychological Association (APA)
Yuan, Ning& Jia, Lili& Geng, Zhen& Wang, Renfeng& Li, Z. Y.& Yang, X. J.…[et al.]. 2017. The Incorporation of Strontium in a Sodium Alginate Coating on Titanium Surfaces for Improved Biological Properties. BioMed Research International،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1139746
Modern Language Association (MLA)
Yuan, Ning…[et al.]. The Incorporation of Strontium in a Sodium Alginate Coating on Titanium Surfaces for Improved Biological Properties. BioMed Research International No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1139746
American Medical Association (AMA)
Yuan, Ning& Jia, Lili& Geng, Zhen& Wang, Renfeng& Li, Z. Y.& Yang, X. J.…[et al.]. The Incorporation of Strontium in a Sodium Alginate Coating on Titanium Surfaces for Improved Biological Properties. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1139746
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139746