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Serum Osteocalcin and Testosterone Concentrations in Adult Males with or without Primary Osteoporosis: A Meta-Analysis
Joint Authors
Liu, Zhong-Yu
Rong, Li-Min
Wen, Chun-Yi
Yang, Yang
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-02
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Osteocalcin (Ocn) and testosterone play important roles in male skeleton.
However, the concentrations of serum osteocalcin and testosterone have never been systematically compared between populations with and without primary male osteoporosis, a common skeletal disorder in adult males.
We searched the PubMed, Embase, and Cochrane Library for relevant studies.
A meta-analysis was performed to compare the serum osteocalcin and testosterone concentrations between primary osteoporotic males and age-matched nonosteoporotic (non-OP) males.
Five case-control studies with 300 adult males were included.
We found no significant difference between cases and controls in serum total osteocalcin (TOcn) [95% confidence interval (CI): −1.25, 1.31; p=0.96] and total testosterone (TT) concentrations [95% CI: −0.88, 4.22; p=0.20].
The level of evidence of this carefully performed meta-analysis is 3a according to Oxford (UK) CEBM Levels of Evidence.
Future well-designed studies with larger sample size and better standardization of Ocn assay are awaited to confirm and update our current findings.
American Psychological Association (APA)
Liu, Zhong-Yu& Yang, Yang& Wen, Chun-Yi& Rong, Li-Min. 2017. Serum Osteocalcin and Testosterone Concentrations in Adult Males with or without Primary Osteoporosis: A Meta-Analysis. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1139751
Modern Language Association (MLA)
Liu, Zhong-Yu…[et al.]. Serum Osteocalcin and Testosterone Concentrations in Adult Males with or without Primary Osteoporosis: A Meta-Analysis. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1139751
American Medical Association (AMA)
Liu, Zhong-Yu& Yang, Yang& Wen, Chun-Yi& Rong, Li-Min. Serum Osteocalcin and Testosterone Concentrations in Adult Males with or without Primary Osteoporosis: A Meta-Analysis. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1139751
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139751