Elevated Cardiovascular Risks among Postmenopausal Women: A Community Based Case Control Study from Nepal

Joint Authors

Parajuli, Narayan Prasad
Khanal, Puspa Raj
Bhetwal, Anjeela
Shakya, Shreena
Ghimire, Sumitra
Pardhe, Bashu Dev
Shakya, Jyotsna
Pathak, Sabala

Source

Biochemistry Research International

Issue

Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2017-05-02

Country of Publication

Egypt

No. of Pages

5

Main Subjects

Chemistry

Abstract EN

Cardiovascular disease (CVD) is one of the leading causes of death worldwide which is more prevalent in women after menopause.

Hormonal changes associated with menopause are accountable for dyslipidemic pattern that causes CVD and associated complications.

Therefore, the present study was commenced to compare the lipid profile in pre- and postmenopausal women.

A descriptive cross-sectional study was conducted at Manmohan Memorial Institute of Health Sciences (MMIHS) from February 2016 to July 2016.

A total of 260 fasting samples were collected from healthy women, 130 from premenopausal and 130 from postmenopausal women, and analyzed for Total Cholesterol (TC), Triacylglycerol (TAG), High Density Lipoprotein Cholesterol (HDL-C), and Low Density Lipoprotein Cholesterol (LDL-C) as per the guideline provided by the reagent manufacturer (Human, Germany).

All the parameters were analyzed by Stat Fax 3300 semi auto analyzer.

TC, TAG, HDL-C, and LDL-C were highly significantly increased in postmenopausal women when compared to premenopausal women.

LDL/HDL ratio was significantly elevated in postmenopausal women than in premenopausal women.

BMI was significantly positively correlated with TC and TAG in both pre- and postmenopausal population and it was positively correlated with HDL-C in premenopausal population while negatively correlated in postmenopausal population.

Since more of the atherogenic lipid parameters are increased in postmenopausal women, they appear to be more prone to have CVD and associated complications in near future.

Hence, it is mandatory to monitor and manage dyslipidemic pattern in every woman experiencing menopause.

American Psychological Association (APA)

Pardhe, Bashu Dev& Ghimire, Sumitra& Shakya, Jyotsna& Pathak, Sabala& Shakya, Shreena& Bhetwal, Anjeela…[et al.]. 2017. Elevated Cardiovascular Risks among Postmenopausal Women: A Community Based Case Control Study from Nepal. Biochemistry Research International،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1139797

Modern Language Association (MLA)

Pardhe, Bashu Dev…[et al.]. Elevated Cardiovascular Risks among Postmenopausal Women: A Community Based Case Control Study from Nepal. Biochemistry Research International No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1139797

American Medical Association (AMA)

Pardhe, Bashu Dev& Ghimire, Sumitra& Shakya, Jyotsna& Pathak, Sabala& Shakya, Shreena& Bhetwal, Anjeela…[et al.]. Elevated Cardiovascular Risks among Postmenopausal Women: A Community Based Case Control Study from Nepal. Biochemistry Research International. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1139797

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1139797